学校首页 公共卫生学院 ·设为首页·院长信箱·管理信箱
邹飞

发布时间:2014-07-21 17:08:05 作者:

照 片：

邹飞.jpg
 
 
职 称：
教授 博导
通信地址：
广东省广州市广州大道北1838号南方医科大学公共卫生与热带医学学院
Email：
zfei@fimmu.com
职 务：
院长
职称级别：
正高
学术任职：
教育部预防医学专业教学指导分委员会委员，中国生理学会应用生理专业委员会副主任委员，中华预防医学会公共卫生教育分会常委，广东省热带医学会理事长，广东省医学会卫生学分会主任委员，广东省预防医学会副会长，广东省毒理学会副理事长
最高学历：
博士
所属科室：
职业卫生与职业医学系
研究方向：

  1. 细胞对环境因素的应答；

  2. 特殊环境医学；
科研项目：

  1. 低氧预适应中Hsp90分子伴侣功能对相互作用底物蛋白的折叠、降解分选机制及作用。国家自然科学基金。2013.01～2016.12

  2. 适度低氧对健康促进作用的机制。国家重点基础研究发展计划（973）课题。2010.9～2015.8

  3. 高原低氧等环境因素损伤适应机理与干预措施。国家重点基础研究发展计划（973）分题。2006.9-2011.8

  4. 抗XXX片临床研究。国家科技重大专项,2008-2010

  5. TRP家族和磷脂酰肌醇的易位及在膜脂筏区的相互作用参与中性粒细胞极性化得研究。国家自然科学基金。2010-2012

  6. 用SSH和单细胞RT-PCR技术研究热适应差显基因与功能。国家自然科学基金。2004-2006

  7. 应急型公共卫生创新人才培养实验区。国家教育部质量工程项目，2007～2011，

  8. 预防医学特色专业。国家教育部质量工程项目，2008-2011

  9. 创新人才培养实验区。国家教育部质量工程项目，2008-2011

  10. ATP敏感性钾通道的非电导功能在神经元缺氧损伤中的保护机制。教育部博士点基金。2008-2011
成果奖励：

  1. 1993年军队科技进步三等奖；条件损伤对运动神经再生的促进作用

  2. 1996年获军队科技进步二等奖；梭曼引起神经肌肉接头阻断机理的研究

  3. 2000年军队科技进步三等奖；钾离子通道活化剂治疗支气管哮喘的实验研究

  4. 2002军队科技进步二等奖；提高热区部队作业能力和中暑防治措施的研究

  5. 2003年军队科技进步二等奖；军事职业危害因素高温对机体的损伤及其对策的研究

  6. 2004年广东省科技进步三等奖；提高热区人员作业能力和中暑防治措施的研究

  7. 2005年获中华医学科技奖一等奖；一个学习记忆有关脑区的发现及其结构和功能的研究

  8. 2009年获广东省教学成果一等奖；高素质应急型公共卫生人才培养的研究与实践

  9. 2014年获广东省教学成果一等奖；“HEALTH”应急型预防医学人才培养模式的研究与实践
代表论文：

  1. Ou Z, Wang G, Li Q, Ma Z, Dai M, Zou F. CRTC3 polymorphisms were associated with the plasma level of total cholesterol and the risks of overweight and hypertriglyceridemia in a Chinese Han population. Mol Biol Rep. 2014 Jan; 41(1): 125-30

  2. Ma S, Cai C, Ma Y, Bai Z, Meng X, Yang X, Zou F, Ge R.Store-operated Ca2+ entry mediated regulation of polarization in differentiated human neutrophil-like HL-60 cells under hypoxia. Mol Med Rep. 2014 Mar;9(3):819-24.

  3. Wu JJ, Yang T, Li X, Xia Y, Zhao Y, Zou F, Jiang YG.4-(methylnitrosamino)-1-(3-pyridyl) -1-butanone Induces Circulating MicroRNA Deregulation in Early Lung Carcinogenesis.Biomed Environ Sci. 2014 Jan;27(1):10-6.

  4. Zhang W, Hu D, Ji W, Yang L, Yang J, Yuan J, Xuan A, Zou F, Zhuang Z. Histone modifications contribute to cellular replicative and hydrogen peroxide-induced premature senescence in human embryonic lung fibroblasts.Free Radic Res. 2014 May;48(5):550-9

  5. Xiao M, Liu YG, Zou MC, Zou F. Sodium Butyrate Induces Apoptosis of Human Colon Cancer Cells by Modulating ERK and Sphingosine Kinase 2. Biomed Environ Sci.  2014 Mar;27(3):197-203.

  6. Wang B, Xiao JL, Ling YH, Meng XJ, Wu B, Yang XY, Zou F. BNIP3 Upregulation by ERK and JNK Mediates Cadmium-Induced Necrosis in Neuronal Cells. Toxicol Sci. 2014 May 13；140(2)：393–402

  7. Tang H, Zhao H, Song J, Dong H, Yao L, Liang Z, Lv Y, Zou F, Cai S. Ethyl pyruvate decreases airway neutrophil infiltration partly through a high mobility group box 1-dependent mechanism in a chemical-induced murine asthma model. Int Immunopharmacol. 2014 May 9;21(1):163-170.

  8. Huang T, Chen S, Han H, Li H, Huang Z, Zhang J, Yin Q, Wang X, Ma X, Dai P, Duan D, Zou F, Chen X. Expression of Hsp90α and cyclin B1 were related to prognosis of esophageal squamous cell carcinoma and keratin pearl formation. Int J Clin Exp Pathol. 2014 Mar 15;7(4):1544-52.

  9. Yang X, Wang B, Zeng H, Cai C, Hu Q, Cai S, Xu L, Meng X, Zou F. Role of the mitochondrial Ca2+ uniporter in Pb2+-induced oxidative stress in human neuroblastoma cells. Brain Res. 2014 Aug 5;1575:12-21.

  10. Xia B, Ren XH, Zhuang ZX, Yang LQ, Huang HY, Pang L, Wu DS, Luo J, Tan YL, Liu JJ, Zou F. Effect of hexavalent chromium on histone biotinylation in human bronchial epithelial cells. Toxicol Lett. 2014 May 21;228(3):241-247.

  11. Guo S, Zhou J, Chen X, Yu Y, Ren M, Hu G, Liu Y, Zou F.Bystander effects of pc12 cells treated with pb2+ depend on ros-mitochondria-dependent apoptotic signaling via gap -junctional intercellular communication.Toxicol Lett.  2014 Jun 21;229 (1):150-157

  12. Zhang H, Li W, Xue Y, Zou F. TRPC1 is involved in Ca2+ influx and cytotoxicity following Pb2+ exposure in human embryonic kidney cells.Toxicol Lett. 2014 Jun 3;229(1):52-58.

  13. Tang H, Zhao H, Song J, Dong H, Yao L, Liang Z, Lv Y, Zou F, Cai S. Ethyl pyruvate decreases airway neutrophil infiltration partly through a high mobility group box 1-dependent mechanism in a chemical-induced murine asthma model. Int Immunopharmacol. 2014 Jul;21(1):163-70.

  14. Ma Z, Wang G, Chen X, Ou Z, Zou F. Association of STAT3 Common Variations with Obesity and Hypertriglyceridemia: Protective and Contributive Effects.Int J Mol Sci.  2014 Jul 10;15(7):12258-12269.

  15. Li J, Yang XF, Ren XH, Meng XJ, Huang HY, Zhao QH, Yuan JH, Hong WX, Xia B, Huang XF, Zhou L, Liu JJ, Zou F.Stable SET knockdown in breast cell carcinoma inhibits cell migration and invasion.Biochem Biophys Res Commun. 2014 Oct 10;453(1):7-12

  16. Huang L, Li B, Tang S, Guo H, Li W, Huang X, Yan W, Zou F.Mitochondrial KATP Channels Control Glioma Radioresistance by Regulating ROS-Induced ERK Activation. Mol Neurobiol. 2014 Sep 24. [Epub ahead of print]

  17. Wang Y, Chu X, Meng X, Zou F.Association of TGF-β1 -509C/T polymorphisms with breast cancer risk: evidence from an updated meta-analysis. Tumour Biol. 2014 35:935–942

  18. Cai C, Tang S, Wang X, Cai S, Meng X, Zou W, Zou F.Requirement for both receptor-operated and store-operated calcium entry in N-formyl-methionine-leucine -phenylalanine-induced neutrophil polarization. Biochem Biophys Res Commun. 2013 Jan 11;430(2):816-21.

  19. Meng X, Cai C, Wu J, Cai S, Ye C, Chen H, Yang Z, Zeng H, Shen Q, Zou F. TRPM7 mediates breast cancer cell migration and invasion through the MAPK pathway.Cancer Lett. 2013 Jun 1;333(1):96-102.

  20. Song J, Zhao H, Dong H, Zhang D, Zou M, Tang H, Liu L, Liang Z, Lv Y, Zou F, Cai S.Activation of PI3K/Akt pathway by CD133-p85 interaction promotes tumorigenic capacity of glioma stem cells. Toxicol Lett. 2013 Apr 6;220(1):8-14.

  21. Zhang D, Peng C, Zhao H, Xia Y, Zhang D, Dong H, Song J, Zhou L, Cai S, Zou F. Induction of thymic stromal lymphopoietin expression in 16-HBE human bronchial epithelial cells by 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3. Int J Mol Med. 2013 Jul;32(1):203-10

  22. Zhou Z, Wu X, Wei Q, Liu Y, Liu P, Ma A, Zou F. Development and validation of a hydrophilic interaction liquid chromatography-tandem mass spectrometry method for the simultaneous determination of five first-line antituberculosis drugs in plasma. Anal Bioanal Chem. 2013 May 30, 405:6323–6335

  23. Li W, Zhang M, Xu L, Lin D, Cai S, Zou F.The apoptosis of non-small cell lung cancer induced by cisplatin through modulation of STIM1. Exp Toxicol Pathol. 2013 Nov;65(7-8):1073-81

  24. Ou Z, Wang G, Li Q, Ma Z, Lin D, Dai M, Zou F. The genetic polymorphisms of Cathepsin S were associated with metabolic disorders in a Chinese Han population. Gene. 2013 Sep 10;526(2):385-9.

  25. Wang Y, Chu X, Meng X, Zou F.Association of X-ray Repair Cross Complementing Group 1 Arg399Gln Polymorphisms with the Risk of Squamous Cell Carcinoma of the Head and Neck: Evidence from an Updated Meta-Analysis. PLoS One. 2013 Oct 30;8(10):e77898.

  26. Wang YJ, Wu SJ, Guo KY, Chen C, Xie Q, Gu WW, Cai L, Zou F.(18)F-FDG uptake by spleen helps rapidly predict the dose level after total body irradiation in a Tibetan minipig model.Eur Radiol. 2012 May 2. [Epub ahead of print]

  27. Zou W, Chu X, Cai C, Zou M, Meng X, Chen H, Zou F. AKT-mediated regulation of polarization in differentiated human neutrophil-like HL-60 cells.Inflamm Res. 2012 May 16. [Epub ahead of print]

  28. Jiang XT, Zhang H, Sheng HF, Wang Y, He Y, Zou F, Zhou HW.Two-Stage Clustering (TSC): A Pipeline for Selecting Operational Taxonomic Units for the High-Throughput Sequencing of PCR Amplicons.PLoS One. 2012;7(1):e30230.

  29. Sun S, Li W, Zhang H, Zha L, Xue Y, Wu X, Zou F. Requirement for store-operated calcium entry in sodium butyrate-induced apoptosis in human colon cancer cells.Biosci Rep. 2012 Feb 1;32(1):83-90.

  30. Xiao M, Liu Y, Zou F.Sensitization of human colon cancer cells to sodium butyrate-induced apoptosis by modulation of sphingosine kinase 2 and protein kinase D.Exp Cell Res. 2012，318:43-52

  31. Wu SJ, Wang YJ, Guo KY, Chen C, Zhao TF, Sun MB, Gu WW, Gao YY, Han HJ, Zou F. Effect of Total Body X-ray Irradiation on Lymph Node in Tibet Minipig.J Radiat Res. 2012 Feb 2;53(1):18-23.

  32. Cai C, Meng X, He J, Wu H, Zou F. Effects of ZD7288 on firing pattern of thermosensitive neurons isolated from hypothalamus. Neurosci Lett. 2012 Jan 11;506(2):336-341.

  33. Zhang H, Li W, Sun S, Yu S, Zhang M, Zou F. Inhibition of sphingosine kinase 1 suppresses proliferation of glioma cells under hypoxia by attenuating activity of extracellular signal-regulated kinase.Cell Prolif. 2012 Apr;45(2):167-75.

  34. Liang Z, Zhao H, Lv Y, Li R, Dong H, Liu L, Xia Y, Hou C, Cai S, Zou F. Moderate accuracy of peripheral eosinophil count for predicting eosinophilic phenotype in steroid-naïve non-atopic adult asthmatics.Intern Med. 2012;51(7):717-22.

  35. Shi L, Xia Y, Zhang M, Yin SJ, Si YX, Qian GY, Lü ZR, Zhou HM, Zou F, Park YD. Trifluoroethanol-Induced Activity and Structural Changes in Bos Taurus Copper- and Zinc-Containing Superoxide Dismutase. Protein Pept Lett. 2011;18(7):726-32.

  36. Zhou ZF, Chen LY, Shen M, Ma AD, Yang XM, Zou F.Analysis of the Essential Oils of Coriandrum sativum Using GC-MS Coupled with Chemometric Resolution Methods. Chem Pharm Bull (Tokyo). 2011;59(1):28-34.

  37. Guo HB, Huang LY, Zou YX, Zou F.Up-regulation of the transient A-type K+ current (IA) in the differentiation of neural stem cells of the early postnatal rat hippocampus.Chin Med J (Engl). 2010 Jul;123(13):1731-5.

  38. Zhou HW, Li DF, Tam NF, Jiang XT, Qin J, Zhang H, Sheng HF, Liu X, Zou F. BIPES, a Cost-Effective High-Throughput Method for Assessing Microbial Diversity. ISME Journal 2011；5：741–749

  39. Jiang YX, Wu JG, Yu KQ, Ai CX, Zou F, Zhou HW.Integrated lysis procedures reduce extraction biases of microbial DNA from mangrove sediment. J Biosci Bioeng. 2011 Feb;111(2):153-7.

  40. Yang Q, Jie Z, Cao H, Greenlee AR, Yang C, Zou F, Jiang Y. Low-level expression of let-7a in gastric cancer and its involvement in tumorigenesis by targeting RAB40C.Carcinogenesis. 2011 May;32(5):713-22.

  41. Hou C, Zhao H, Liu L, Li W, Zhou X, Lv Y, Shen X, Liang Z, Cai S, Zou F. High mobility group protein B1 (HMGB1) in Asthma: comparison of patients with chronic obstructive pulmonary disease and healthy controls.Mol Med. 2011,17(7-8)：807-815

  42. Hou C, Zhao H, Li W, Liang Z, Zhang D, Liu L, Tong W, Cai SX, Zou F. Increased heat shock protein 70 levels in induced sputum and plasma correlate with severity of asthma patients. Cell Stress Chaperones. (2011) 16；663–671

  43. Sheng Q, Zou HC, Lü ZR, Zou F, Park YD, Yan YB, Yao SJ. Effects of acrylamide on the activity and structure of human brain creatine kinase.Int J Mol Sci. 2009 Nov 2010(10): 4210-22.

  44. Zhi-Rong Lü, Sang Ho Oh, Shan-Shan Zhou,He-Chang Zou,Daeui Park, Seong Jin Park,Hong-Wei Zhou, Jong Bhak,Yong-Doo Park,and Fei Zou：Structural analysis and inhibitory kinetics of brain type creatine kinase by sodium dodecyl sulfate. Appl Biochem Biotechnol. 2010 Mar;160(3):831-42.

  45. Hang Mu,Zhi-Rong Lu,Daeui Park,Byoung-Chul Kim,Jong Bhak,Fei Zou,Jun-Mo Yang,Sen Li,Yong-Doo Park,He-Chang Zou,Hai-Meng Zhou: Kinetics of Zn(2+)-induced Brain Type Creatine Kinase Unfolding and Aggregation. Appl Biochem Biotechnol. 2010 Mar 160:1309–1320.

  46. Xue-Qiang Wu,Jun Wang, Zhi-Rong Lu,Hong-Min Tang, Daeui Park,Sang-Ho Oh,Jong Bhak,Long Shi, Yong-Doo Park, and Fei Zou：Alpha-glucosidase folding during urea denaturation: enzyme kinetics and computational prediction. Appl Biochem Biotechnol. 2010 Mar;160(5):1341-55.

  47. Lu ZR, Shi L, Wang J, Park D, Bhak J, Yang JM, Park YD, Zhou HW, Zou F.The Effect of Trifluoroethanol on Tyrosinase Activity and Conformation: Inhibition Kinetics and Computational Simulations. Appl Biochem Biotechnol. 2010 Apr;160(7):1896-908.

  48. Wang Z, Liu Y, Han N, Chen X, Yu W, Zhang W, Zou F. Profiles of oxidative stress-related microRNA and mRNA expression in auditory cells. Brain Res. 2010 ；1346:14-25

  49. Zhifeng ZHOU, Jufeng YE, Lingyun CHEN, Ande MA and Fei ZOU, Simultaneous Determination of Ropivacaine, Bupivacaine and Dexamethasone in Biodegradable PLGA Microspheres by High Performance Liquid Chromatography, YAKUGAKU ZASSHI, 2010, 130(8)：1061-1068

  50. Zhou Z, Chen L, Liu P, Shen M, Zou F. Simultaneous Determination of Isoniazid, Pyrazinamide,Rifampicin and Acetylisoniazid in Human lasma by High-Performance Liquid Chromatography. Anal Sci. 2010;26(11):1133-1138

  51. Jin-Ya Wu, Xiao-Tao Jiang, Yun-Xia Jiang, Su-Ying Lu, Fei Zou and Hong-Wei Zhou. Effects of polymerase, template dilution and cycle number on PCR based 16S rRNA diversity analysis using the deep sequencing method. BMC Microbiology 2010, 10:255-261

  52. Lu SY, Zhang YL, Geng SN, Li TY, Ye ZM, Zhang DS, Zou F, Zhou HW.High Diversity of Extended-spectrum Beta-lactamase-producing Bacteria in an Urban River Sediment Habitat.Appl Environ Microbiol. 2010 Sep;76(17):5972-6.


Copyright © 南方医科大学 公共卫生学院
电子邮件：gwxy@fimmu.com 联系电话：020-62789130
网站制作维护：网络中心