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孟晓静

发布时间:2014-07-21 17:08:00 作者:

照 片:

孟晓静.jpg

 
 
职 称:
教授 博导
通信地址:
南方医科大学公共卫生与热带医学学院职业卫生与职业医学系
Email:
xiaojingmeng@smu.edu.cn
职 务:
副主任
职称级别:
正高
学术任职:
中国毒理学会神经毒理专业委员会青年委员广东省药理学会委员
最高学历:
博士
所属科室:
职业卫生与职业医学系
研究方向:
1. 环境因素与肿瘤2. 细胞运动3. 细胞信号转导
科研项目:
1.环境铅暴露致儿童脑发育损伤的机制研究 “973”分题 2012.1-2017.12 分课题课题骨干
2.TRPC1蛋白分子参与中性粒细胞极性化的作用机制 教育部留学回国人员基金2011.1-2013.12 负责人
3.TRPC1蛋白分子参与中性粒细胞极性化的作用机制 国家自然科学基金 2009.1-2011.12负责人
4. Prevention of Breast Cancer Progression with Conjugated Linoleic Acid (共轭亚油酸对乳腺癌防治机制的研究) 美国肿瘤研究协会-雅芳国际基金2005.11-2007.11负责人
成果奖励:
 
代表论文:
1.Xiaojing Meng, Chunqing Cai, Jiguo Wu, Shaoxi Cai, Changsheng Ye, Zhenzhuo Yang,Qiang Shen, Fei Zou. TRPM7 mediates breast cancer cell migration and invasion through the MAPK pathway. Cancer Lett. Cancer Lett. 2013 Jun 1;333(1):96-102. PMID: 23353055(IF:4.238)
2.Xiaojing Meng, Suzanne Shoemaker, Sibel O. McGee, Margot M. Ip. t10,c12-conjugated linoleic acid stimulates mammary tumor progression in her2/erbB2 mice through activation of both proliferative and survival pathway. Carcinogenesis. 2008 May; 29(5):1013-21. Epub 2008 Mar 13. PMID: 18339686(IF:5.406)
3.Chunqing Cai, Shihao Tang, Xubu Wang, Shaoxi Cai, Xiaojing Meng, Wenying Zou, Fei Zou. Requirement for both receptor-operated and store-operated calcium entry in N-formyl-methionine-leucine-phenylalanine-induced neutrophil polarization. Biochem Biophys Res Commun. 2013 Jan 11;430(2):816-21. PMID: 23219814(IF:2.484)
4.Wenying Zou, Xiaojing Meng, Chunqing Cai, Mengchen Zou, Shihao Tang, Xinwei Chu, Xubu Wang, Fei Zou. Store-operated Ca2+ entry (SOCE) plays a role in the polarization of neutrophil-like HL-60 cells by regulating the activation of Akt, Src, and Rho family GTPases. Cell Physiol Biochem. 2012;30(1):221-37. PMID: 22759969(IF:2.857)(co-author)
5.Chunqing Cai, Xiaojing Meng,Junchu He, Hangyu Wu, Fei Zou. Effects of ZD7288 on firing pattern of thermosensitive neurons isolated from hypothalamus.Neurosci Lett. 2012 Jan 11;506(2):336-41. Epub 2011 Dec 2. (IF:2.200)(co-author)
6.Yung-Chun Hsu, Xiaojing Meng, Lihui Ou, Margot M. Ip. Activation of the AMP-activated protein kinase-p38 MAP kinase pathway mediates apoptosis induced by conjugated linoleic acid in p53-mutant mouse mammary tumor cells. Cell Signal. 2010 Apr;22(4):590-9. PMID: 19932174 (IF: 4.305)
7.Dongliang Zhao, Xiaojing Meng, Chunqing Cai, Chunhua Yuan, Fei Zou. Temperature pretreatment alters the polarization response of human neutrophils to the chemoattractant N-formyl-Met-Leu-Phe. Inflammation. 2009 February, 32(1): 47-56 PMID: 19067145(IF:1.000)(co-author)
8.Bin Wang, Wenjun Li, Xiaojing Meng, Fei zou. Hypoxia up-regulates vascular endothelial growth factor in U-87 MG cells: involvement of TRPC1. Neurosci Lett. 2009 Aug 14;459(3):132-6. PMID: 19446005 (IF:2.200)
9.Lihui Ou,Yue Wu, Xiaojing Meng, Yung-Chun Hsu,Clement Ip, Margot M. Ip. Apoptosis induced by t10,c12-conjugated linoleic acid is mediated by an atypical endoplasmic reticulum stress response. Journal of lipid research. 2008 May;49(5):985-94. Epub 2008 Feb 8. PMID: 18263853(IF:4.336)