职 称:教授 博士生导师
通信地址:广州市白云区广州大道北1838号
Email:xiexiaoli1999@126.com
职称级别:正高
最高学历:博士研究生
研究方向:
环境与健康、发育毒性
科研项目:
先后主持/主要参与国家级、省部级科研项目多项。
代表论文:(近三年)
1. Xu LL, Chen YK, Zhang QY, Chen LJ, Zhang KK, Li JH, Liu JL, Wang Q*, Xie XL* (谢晓利). Gestational exposure to GenX induces hepatic alterations by the gut-liver axis in maternal mice: A similar mechanism as PFOA. Sci Total Environ. 2022 May 10;820:153281. (IF=10.753, 小类I区)
2. Zhao D, Wang Q, Zhou WT, Wang LB, Yu H, Zhang KK, Chen LJ, Xie XL*(谢晓利). PCB52 exposure alters the neurotransmission ligand-receptors in male offspring and contributes to sex-specific neurodevelopmental toxicity. Environ Pollut. 2020 Sep; 264:114715. (IF=8.071, 小类I区)
3. Tan XH, Zhang KK, Xu JT, Qu D, Chen LJ, Li JH, Wang Q*, Wang HJ*, Xie XL*(谢晓利). Luteolin alleviates methamphetamine-induced neurotoxicity by suppressing PI3K/Akt pathway-modulated apoptosis and autophagy in rats. Food Chem Toxicol. 2020 Mar;137:111179. (IF=6.025, 小类I区)
4. Chen LJ, Zhi X, Zhang KK, Wang LB, Li JH, Liu JL, Xu LL, Yoshida JS, Xie XL*(谢晓利), Wang Q*. Escalating dose-multiple binge methamphetamine treatment elicits neurotoxicity, altering gut microbiota and fecal metabolites in mice. Food Chem Toxicol. 2021 Feb;148:111946. (IF=6.025, 小类I区)
5. Zhang KK#, Liu JL#, Chen LJ, Li JH, Yang JZ, Xu LL, Chen YK, Zhang QY, Li XW, Liu Y, Zhao D, Xie XL*(谢晓利), Wang Q*. Gut microbiota mediates methamphetamine-induced hepatic inflammation via the impairment of bile acid homeostasis. Food Chem Toxicol. 2022 Aug;166:113208. (IF=6.025, 小类I区)
6. Xu LL, Zhang QY, Chen YK, Chen LJ, Zhang KK, Wang Q, Xie XL*(谢晓利). Gestational PCB52 exposure induces hepatotoxicity and intestinal injury by activating inflammation in dam and offspring mice: A maternal and progeny study. Environ Pollut. 2022 Nov 15;313:120186. (IF=9.988, 小类II区)
7. Wang LB, Chen LJ, Wang Q*, Xie XL*(谢晓利). Silencing the Tlr4 Gene Alleviates Methamphetamine-Induced Hepatotoxicity by Inhibiting Lipopolysaccharide-Mediated Inflammation in Mice. Int J Mol Sci. 2022 Jun 18;23(12):6810. (IF=6.208, 小类II区)
8. Wang LB, Xu LL, Chen LJ, Zhang KK, Zhang QY, Chen YK, Li JH, Liu JL, Wang Q*, Xie XL*(谢晓利). Methamphetamine induces intestinal injury by altering gut microbiota and promoting inflammation in mice. Toxicol Appl Pharmacol. 2022 May 15;443:116011. (IF=4.460, 小类II区)
9. Chen LJ, He JT, Pan M, Liu JL, Zhang KK, Li JH, Wang LB, Xu LL, Chen YK, Zhang QY, Li DR*, Xu JT*, Xie XL*(谢晓利). Antibiotics Attenuate Methamphetamine-Induced Hepatotoxicity by Regulating Oxidative Stress and TLR4/MyD88/Traf6 Axis. Front Pharmacol. 2021 Jul 26;12:716703. (IF=5.988, 小类II区)
10. Xie XL*(谢晓利), Zhou WT, Zhang KK, Yuan Y, Qiu EM, Shen YW, Wang Q*. PCB52 induces hepatotoxicity in male offspring through aggravating loss of clearance capacity and activating the apoptosis: Sex-biased effects on rats. Chemosphere. 2019 Jul;227:389-400. (IF=5.778, 小类II区)