一、基本信息
姓名：彭鸿娟
职称：教授
联系邮箱：floriapeng@hotmail.com
二、学习经历
1989.9-1993.7 厦门大学，动物学专业，学士
1993.9-1996.7 中山大学，动物学专业，硕士
2000.9-2003.7 中山大学，生化与分子生物学专业，博士
2006.11-2009.9 Virginia Polytechnic Institute and State University，博士后
三、拟招收博士后开展的研究方向
1.病原-宿主互作机制研究；
2.重要蚊媒传染病防控研究
四、主要学术任职
1. 中国预防医学学会医学寄生虫学分会，青年委员；
2. 中国动物学会寄生虫学专业委员会，理事；
3. 广东省寄生虫学学会，常务理事；
4. 广东省热带医学学会，常务理事
五、主要获奖情况
1. 广东省“珠江学者”特聘教授，广东省教育厅，2014；
2. 广东省“千百十人才工程省级培养对象与先进个人，广东省教育厅，2010-2014；
3. 广东省教育教学成果一等奖（第一完成人）“慕课背景下《医学寄生虫学》精品课程的建设与实践”，2018.11
4. 广东省科技成果三等奖（第一完成人）“血吸虫新基因的筛选、鉴定与应用”，2005.08
六、代表性论文
第一作者论文
1. Peng H-J#, Henkels KM#, Mahankali M, Dinauer MC. Gomez-Cambronero J (2011) Evidence For Two Crib Domains In Phospholipase D2 (Pld2) That The Enzyme Uses to Specifically Bind to The Small GTPase Rac2. J Bio.Chem. 286(18): 16308-20
2. Peng H-J#, Henkels KM#, Mahankali M, Marchal C, Bubulya P, Dinauer MC, Gomez-Cambronero J (2011) The dual effect of Rac2 on phospholipase D2 regulation that explains both the onset and termination of chemotaxis. Mol Cell Biol. 31(11):2227-40.
3. Peng H-J#，Chen X-G#，Lindsay DS*，A Review: Competence, Compromise, And Concomitance-Reaction Of The Host Cell To Toxoplasma Gondii Infection And Development. J Parasitol，2011.8.01，97（4）：620~628
4. Peng H-J#，Zhang C(#)，Wang C-M，Chen X-G*，Current Status and Challenge of Human Parasitology Teaching in China. Pathog Glob Health，2012.12.11，106（7）：386~390
5. Peng H-J，Lai H-B，Zhang Q-L，Xu B-Y，Zhang H，Liu W-H，Zhao W，Zhou Y-P，Zhong X-G，Jiang S，Duan J-H，Yan G-Y，He J-F(*)，Chen, Xiao-Guang，A local outbreak of dengue caused by an imported case in Dongguan China. BMC Public Health，2012.1.26，12（1）:83
通讯作者论文
6. Xia J, Kong L, Zhou L-J, Wu S-Z, Yao L-J, He C, He CY, Peng H-J* (2018) Genome-Wide Bimolecular Fluorescence Complementation- Based Proteomic Analysis of Toxoplasma gondii ROP18’s Human Interactome Shows Its Key Role in Regulation of Cell Immunity and Apoptosis. Front. Immunol. 9:61. doi: 10.3389/fimmu.2018.00061
7. Wei, H., Zhou, L., Wu, S., Li, D., Deng, S., and Peng, H. (2019). Host cell Rac1 GTPase facilitates Toxoplasma gondii invasion. Sci China Life Sci 62, https://doi.org/10.1007/s11427-019-9564-0
8. Zhou LJ, Chen M, Puthiyakunnon S, He C, Xia J, He C, Deng SQ，Peng HJ. Toxoplasma gondii ROP18 inhibits human glioblastoma cell apoptosis through a mitochondrial pathway by targeting host cell P2X1.Parasites & Vectors. 2019, 12:284 https://doi.org/10.1186/s13071-019-3529-1
9. He C, Kong L,Puthiyakunnon S, Wei HX, Zhou LJ, Peng H-J*. iTRAQ-based phosphoproteomic analysis reveals host cell's specific responses to Toxoplasma gondii at the phases of invasion and prior to egress. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 2018, Dec 18;1867(3):202-212. doi: 10.1016/j.bbapap.2018.12.004
10. He C, Kong L, Zhou L, Xia J, Wei H, Liu M, Peng H* Host Cell Vimentin Restrains Toxoplasma gondii Invasion and Its hosphorylation Is Partly Regulated by TgROP18 Interaction. Int J Biol Sci. 2017; 13(9):1126-1137 doi:10.7150/ ijbs.21247.
11. Wei H, Jiang S, Chen L, He C, Wu S, Peng H* Characterization of Cytosine Methylation and the DNA Methyltransferases of Toxoplasma gondii. Int J Biol Sci. 2017; 13(4):458-70. doi:10.7150/ijbs.18644.
12. He C, Chen AY, Feng XS, Wei HX, Jiang SC, Xia J, Deng SQ, Wang XJ, Peng H-J* Phosphoproteome of Toxoplasma gondii Infected Host Cells Reveals Specific Cellular Processes Predominating in Different Phases of Infection. Am J Trop Med Hyg. 2017.DOI:104269/ajtmh.16-0901
13. Na RH, Zhu GH, Luo JX, Meng XJ, Cui L, Peng HJ*, Chen XG*, Gomez – Cambronero J. Enzymatically active Rho and Rac small-GTPases are involved in the establishment of the vacuolar membrane after Toxoplasma gondii invasion of host cells. BMC Microbiol. 2013,13:125 doi:10.1186/1471-2180-13-125.
14. Deng SQ, Zou WH, Li DL, Chen JT, Huang Q, Zhou LJ, Tian XX, Chen YJ, Peng HJ*. Expression of Bacillus thuringiensis toxin Cyt2Ba in the entomopathogenic fungus Beauveria bassiana increases its virulence towards Aedes mosquitoes. PLoS Negl Trop Dis. 2019 Jul 15;13(7):e0007590.
15. Deng S, Huang Q, Wei H, Zhou L, Yao L, Li D, Wu S, Chen J, Peng H*. Beauveria bassiana infection reduces the vectorial capacity of Aedes albopictus for the Zika virus. Journal of Pest Science. 2019, 92（2）:781-789. https://doi.org/10.1007/s10340-019-01081-0
16. Li XL, Wei HX, Zhang H, Peng HJ*, Lindsay DS*( 2014) A Meta Analysis on Risks of Adverse Pregnancy Outcomes in Toxoplasma gondii Infection. PLoS One. 9(5):e97775. doi: 10.1371/journal.pone. 0097775. eCollection 2014.
17. Wei HX, Wei SS, Lindsay DS, Peng HJ*. A Systematic Review and Meta-Analysis of the Efficacy of Anti-Toxoplasma gondii Medicines in Humans. PLoS One. 2015;10(9):e0138204. doi: 10.1371/journal.pone.0138204. eCollection 2015
18. Wei HX, He Cheng, Yang PL, Lindsay DS*, Peng HJ*. Relationship Between Cat Contact and Infection by Toxoplasma gondii in Humans: A Meta-Analysis. Comp. Parasitol. 2016; 83(1): 11–19
19. Xia J, Cheng XY, Wang XJ, Peng HJ* Association between Toxoplasma gondii types and outcomes of human infection: a review and meta-analysis. Acta Microbiologica et Immunologica Hungarica. 2017，64（3）：229-244. IF:0.9;
20. Shen SQ, Wei HX, Fu YH, Zhang H, Mo QY, Wang XJ, Deng SQ, Zhao W, Liu Y, Feng XS, Chen W, Peng HJ*. Multiple Sources of Infection and Potential Endemic Characteristics of the Large Outbreak of Dengue in Guangdong in 2014. Scientific Reports.2015;5:16913.
21. Zhou LJ，Xia J，Wei HX，Liu XJ，Peng HJ* Risk of drug resistance in Plasmodium falciparum malaria therapy-a systematic review and meta-analysis. Parasitol Res. 2017.2.15，116（2）:781-788 Xia J, Jiang SC, Peng HJ*.Association between Liver Fluke Infection and Hepatobiliary Pathological Changes: A Systematic Review. PLOS one. 2015 (7): e0132673. DOI: 10.1371/journal.pone.0132673
22. Wang XJ, Jiang SC, Wei HX, Deng SQ, He C, Peng HJ*.The Differential Expression and Possible Function of Long Noncoding RNAs in Liver Cells Infected by Dengue Virus. Am J Trop Med Hyg. 2017 Oct 2. 97(6):1904-1912. doi: 10.4269/ajtmh.17-0307. Wang XJ, Wei HX, Jiang SC, He C, Xu XJ, Peng HJ*. Evaluation of aminotransferase abnormality in dengue patients: A meta analysis. Acta Trop. 2016;156:130-6. doi: 10.1016/j.actatropica.2015.12.013
23. Deng SQ, Cai QD, Deng MZ, Huang Q, Peng HJ*. Scorpion neurotoxin AaIT-expressing Beauveria bassiana enhances the virulence against Aedes albopictur mosquitoes. AMB Express. 2017.7:121
24. Huang Q, Hu L, Liao QB, Xia J, Wang QR, Peng HJ*. Spatiotemporal analysis of the malaria epidemic in mainland China, 2004-2014. Am J Trop Med Hyg. 2017. 97(2):504-513. DOI:104269/ajtmh.16-0711
25. Zhang H. He Z, Zeng W*, Peng HJ* Roles of Interferons in Pregnant Women with Dengue Infection: Protective or Dangerous Factors. Canadian Journal of Infectious Diseases and Medical Microbiology, 2017; 17:1671607. doi: 10.1155/2017/1671607.
26. Wu XB, Na RH, Wei SS, Zhu JS, Peng HJ* Distribution of Tick-borne Diseases in China. Parasites & Vectors. 2013, 6:119 doi:10.1186/1756-3305-6-119