一、基本信息
姓名：廖文镇
职称：教授
联系邮箱：wenzhenliao@163.com
联系电话：13580077771
二、学习经历（本科起）
1. 2003. 09 – 2007.06，佛山科学技术学院，生物技术，学士
2. 2007.09 – 2010.06，暨南大学，微生物学，硕士，导师：李弘剑
3. 2012.09 – 2015.06，华南理工大学，食品科学，博士，导师：宁正祥
三、拟招收博士后开展的研究方向
1. 营养与慢性病干预：主要从事营养活性物质构效关系及其在慢性病防治方面的研究。
四、主要学术任职
1. 广东省肿瘤康复专业委员会常务委员、创始会员；
2. 广东省健康管理学会食品安全与营养健康专业委员会常务委员；
3. 中国营养学会特殊营养分会委员；
4. 广东食品学会青年委员；
5. 广东营养学会青年委员。
五、 主要获奖情况
1. 2014.09 华南理工大学秋季优秀博士学位论文创新基金, 二等奖;
2. 2015.05 欣博盛国家奖学金;
3. 2015.07 Best Graduate paper Award (Issued by North American Jiangnan University Alumi & Friends As-socation).
六、代表性论文
第一作者论文
1. Liao WZ, Ning ZX, Chen LY, Wei QY, Yuan ED, Yang JG*, Ren JY*. Intracellular Antioxidant Detoxifying Effects of Diosmetin on 2,2-Azobis (2- amidinopropane) Dihydrochloride (AAPH)-Induced Oxidative Stress through Inhibition of Reactive Oxygen Species Generation. Journal of Agricultural and Food Chemistry, 2014, 62: 8648-8654.
2. Liao WZ, Luo Z, Liu D, Ning ZX, Yang JG*, Ren JY*. Structure Characterization of a Novel Polysaccharide from Dictyophora indusiata and Its Macrophage Immunomodulatory Activities. Journal of Agricultural and Food Chemistry, 2015, 63: 535-544.
3. Liao WZ, Lai T, Dong CB, Yu Z*, Ren JY*. Novel Walnut Peptide– Selenium Hybrids with Enhanced Anticancer Synergism: Facile synthesis and mechanistic investigation of anticancer activity. International Journal of Nanomedicine, 2016; 11: 1305–1321.
4. Liao WZ, Lu YJ, Fu JN, Ning ZX, Yang JG*, Ren JY*. Preparation and Characterization of Dictyophora indusiata Polysaccharide-Zinc Complex and Its Augmented Antiproliferative Activity on Human Cancer Cells. Journal of Agricultural and Food Chemistry, 2015, 63, 6525−6534.
5. Liao WZ#, Lai T #, Chen LY #, Fu JN, Sreeprasad TS, Yu Z*, Ren JY*#. Synthesis and Characterization of Walnut Peptides-Zinc Complex and Its Antiproliferative Ability against Human Breast Carcinoma Cells through Induction of Apoptosis. Journal of Agricultural and Food Chemistry, 2016, 64: 1509-1519.
6. Liao WZ, Yu Z, Lin Z, Lei Z, Ning Z, Regenstein JM, Yang JG*, Ren J.*. Biofunctionalization of Selenium Nanoparticle with Dictyophora Indusiata Polysaccharide and Its Antiproliferative Activity through Death-Receptor and Mitochondria-Mediated Apoptotic Pathways. Scientific Reports, 2015, 5: 18629.10.
7. Liao WZ#, Li W#, Zhang TT*, Kirberger M, Liu J, Wang P, Chen W, Wang Y*. Powering Up the Molecular Therapy of RNA Interference by Novel Nanoparticles. Biomaterials Science. 2016, 4, 1051-1061
8. Liao WZ, Ning ZX, Ma L, Yin X, Wei QY, Yuan ED, Yang JG*, Ren JY*. Recrystallization of Dihydromyricetin from Ampelopsis grossedentata and Its Anti- Oxidant Activity Evaluation. Rejuvenation Research, 2014, 17（5）: 422-429.
9. Liao WZ#, Chen L Y#, Ma X, Jiao R, Li X, Wang Y*. Protective effects of kaempferol against reactive oxygen species-induced hemolysis and its antiproliferative activity on human cancer cells. European Journal of Medicinal Chemistry, 2016, 114: 24-32.
10. Liao WZ, Gu LJ, Zhu ZS, Zheng YM, Zhao MM, Liang M, Ren JY*. Analysis of quantitative structure–activity relationship of glutathione-derived peptides based on different free radical scavenging assays. MedChemComm, 2016, 7, 2083-2093.
11. Liao WZ, Chen LY, Yu B, Lei Z, Wu X, Yang JG*, Ren JY*. Cell-based evaluation of a novel Dictyophora indusiata polysaccharide against oxidative induced erythrocyte hemolysis, Cellular and Molecular Biology. 2016, 62 (1): 38-44.
12. Liao WZ, Liu ZJ, Zhang TT, Sun SX, Ye JF, Li ZY, Mao LZ, Ren JY. Enhancement of Anti-Inflammatory Properties of Nobiletin in Macrophages by a Nano- Emulsion Preparation. Journal of agricultural and food chemistry. 2017,66(1): 91-98
13. Liao WZ, Zhang TT, Gao LQ, Lee SS, Xu J, Zhang H, Yang ZG, Liu ZY*, Li W*. Integration of Novel Materials and Advanced 'Omics' Technologies into New Vaccine Design. Current Topics in Medicinal Chemistry, (2017) 17: 2286.
通讯作者论文（勿与第一作者论文重复）
1. Ren JY, Zheng YM., Lin ZH, Han X, Liao WZ*. Macroporous resin purification and characterization of flavonoids from Platycladus orientalis (L.) Franco and their effects on macrophage inflammatory response, Food Function. 2017, 8, (1), 86-95.
2. Zhang TT, Li W, Meng GM, Wang P, Liao WZ*. Strategies for transporting nanoparticles across the blood-brain barrier, Biomaterials Science. 2016, 4, (2), 219-29.
3. Lin ZH, Liao WZ*, Ren JY*. Physicochemical Characterization of a Polysaccharide Fraction from Platycladus orientalis (L.) Franco and Its Macrophage Immunomodulatory and Anti-Hepatitis B Virus Activities, Journal of agricultural and food chemistry. 2016, 64, (29), 5813-23.
4. Yu ZQ, Cai Z, Chen QL, Liu MH, Ye L, Ren JY, Liao WZ*, Liu SW*. Engineering β-sheet peptide assemblies for biomedical applications. Biomaterials Science. 2016, 4, 365–374.
5. Yang L, Li W, Kirberger M, Liao WZ*, Ren JY*. Design of nanomaterial based systems for novel vaccine development. Biomaterials Science. 2016, 4(5): 785-802.6. Li Q, Li W, Xu J, Ning Z, Ren J, Liao WZ*. Structural Design and Physicochemical Foundations of Hydrogels for Biomedical and Pharmaceutical Applications. Current medicinal chemistry. (2018) 25: 963.
7. Yuan MM, Meng W, Liao WZ*, Lian S*. Andrographolide Antagonizes TNF- α-Induced IL-8 via Inhibition of NADPH Oxidase/ROS/NF-κB and Src/MAPKs/AP-1 Axis in Human Colorectal Cancer HCT116 Cells. Journal of agricultural and food chemistry, 2018, 66(20), 5139-5148 （Research article）
8. Xia Y, Yuan M, Li S, Thuan UT, Nguyen TT, Kang TW, Liao WZ*，Lian S*, Jung DY*. Apigenin suppresses IL-1β-induced expression of urokinase- type plasminogen activator receptor by inhibiting MAPK-mediated AP-1 and NF-кB signaling in human bladder cancer T24 cells. Journal of agricultural and food chemistry. 2018, 66 (29), pp 7663-7673
9. Cao Y, Li ZY, Mao LZ, Cao HH, Kong JJ, Yu B, Yu CM*, Liao WZ*. The use of proteomic technologies to study molecular mechanisms of multidrug resistance in cancer. European Journal of Medicinal Chemistry, 2019, Jan 15; 162: 423-434.
10. Wang K#, Hao YT#, Wang YN , Chen JY, Mao LZ, Deng YD, Chen JL , Yuan SJ, Zhang TT *, Ren JY*, Liao WZ*. Functional hydrogels and their application in drug delivery, biosensors, and tissue engineering. International Journal of Polymer Science. https://doi.org/10.1155/2019/3160732.
11. Cao Y*, Gong Y, Liao WZ*, Luo Y, Wu C, Wang M, Yang Q. A review of cardiovascular toxicity of TiO2, ZnO and Ag nanoparticles (NPs). BioMetals, 2018, 1- 20.
12. Yuan MM#, Song XX#, Lv W#, Xin Q, Wang L, Gao Q, Zhang GC, Liao WZ*, Lian S*, Jing T*. Effect of anacardic acid against echinococcosis through inhibition of VEGF-induced angiogenesis. Veterinary Research. (2019) 50: 3.
13. Ren JY, Hou CL, Shi CC, Lin ZH, Liao WZ*, Yuan ED*. A polysaccharide isolated and purified from Platycladus orientalis (L.) Franco leaves, characterization, bioactivity and its regulation on macrophage polarization. Carbohydrate Polymers. https://doi.org/10.1016/j.carbpol.2019.03.003.
14. Bai ZM#, Wei J#, Yu CM*, Han XS, Qin XF, Zhang CW, Liao WZ*, Li L*, Huang W. Non-viral nanocarriers for intracellular delivery of microRNA therapeutics. Journal of Materials Chemistry B. 2019, 7, 1209-1225.
15. Ye JF#, Wang XD#, Wang K, Deng YD, Yang YC, Ali R, Chen FL, Wu ZJ, Liao WZ*, Mao LM*. A novel polysaccharide isolated from Flammulina velutipes , characterization, macrophage immunomodulatory activities and its impact on gut microbiota in rats. Journal of Animal Physiology and Animal Nutrition. 2020. 104(2), 735-748.
16. Zhang RJ#, Yuan SJ#, Ye JF, Wang XD, Zhang XD, Shen J, Yuan MM* and Liao WZ*. Polysaccharide from flammuliana velutipes improves colitis via regulation of colonic microbial dysbiosis and inflammatory responses. International Journal of Biological Macromolecules. 2020. 149, 1252-1261.
17. Zhang RJ#, Chen J#, Mao LZ, Guo YJ, Hao YT, Deng YD, Han X, Li QJ*, Liao WZ*, Yuan MM*. Nobiletin Triggers Reactive Oxygen Species-Mediated Pyroptosis through Regulating Autophagy in Ovarian Cancer Cells. Journal of agricultural and food chemistry, 2020,68(5) 1326−1336.
18. Deng YD#, Zhang XD#, Shen HB, He QN, Wu ZJ, Liao WZ*, Yuan MM*. Application of the Nano-Drug Delivery System in Treatment of Cardiovascular Diseases. Frontiers in Bioengineering and Biotechnology. 2020. 31(7), 489.
19. Deng YD#, Chen, JY#, Huang JY, Yang XS, Zhang XD, Yuan SJ, Liao WZ*. Preparation and characterization of cellulose/flaxseed gum composite hydrogel and its hemostatic and wound healing functions evaluation. Cellulose. 2020. 27(7), 3971-3988.
20. Liao XS#,Yang XS#, Deng H, Hao YT, Mao LZ, Zhang RJ, Liao WZ* and Yuan MM* Injectable Hydrogel-Based Nanocomposites for Cardiovascular Diseases. Frontiers in Bioengineering and Biotechnology. 2020. 8, 251.
21. Deng YD#, Yang XS#, Zhang XD, Cao HH , Mao LZ, Yuan MM*, Liao WZ*. Novel fenugreek gum-cellulose composite hydrogel with wound healing synergism: facile preparation, characterization and wound healing activity evaluatio. International Journal of Biological Macromolecules. 2020.