汪枭睿

姓名：汪枭睿

职称：教授

联系邮箱：wxr114@smu.edu.cn

v 学习经历：

2010.09-2016.03 中国科学技术大学，化学，博士

2006.09-2010.07 合肥工业大学，高分子材料与工程，学士

v 工作经历：

2018.04-至今 南方医科大学，教授，博士生导师

2016.04-2018.04 复旦大学，博士后

v 研究方向：

    主要从事生物医用纳米药物的设计制备及其体内纳米生物效应的研究，所涉及的研究工作涵盖材料化学、纳米医药、纳米生物学等多学科的融合交叉，以新型智能医用纳米药物体系的开发创制为出发点，深入研究纳米药物在生物体内的纳米生物效应，优化提升纳米药物在体内应用中的生物学性能。

    欢迎有生物学、化学或药学等背景的本科生与研究生加盟课题组。

    本课题组长期招聘博士后研究人员（年薪32-45万），欢迎致电咨询或前来实验室参观了解。

v 主要学术任职

中国技术市场协会医疗器械科技创新专业委员会委员

v 主要科研项目：

[1]国家自然科学基金, 面上项目，2024-01 至 2027-12，50万元, 主持

[2]国家自然科学基金, 面上项目，2020-01 至 2023-12，57万元, 主持

[3]国家自然科学基金, 青年科学基金项目，2020-01 至 2022-12，25万元, 主持

[4]南方医科大学高层次人才引进科研启动项目，2018-06 至 2023-06，300 万元，主持

[5]广东省自然科学基金，面上项目，2024-01 至 2026-12，15万元, 主持

[6]广州市科技基础与应用基础研究项目，2022-04 至 2024-03，5 万元，主持

v 指导学生获得的科研项目

[1]国家自然科学基金，青年科学基金项目，2024.01 - 2026.12，30 万元，谭国柱主持

[2]中国博士后科学基金，面上项目，2024，8 万元，谭国柱主持

[3]中国博士后科学基金，面上项目，2024，8 万元，苗贵凤主持

v 代表性论文：

[1] G. Z. Tan, Q. J. Zhong, J. B. Zhang, P. Y. He, X. X. Zhao, G. F. Miao, Y. F. Xu, X. R. Wang*, "A general strategy towards activatable nanophotosensitizer for phototoxicity-free photodynamic therapy", Theranostics, 2024, DOI: 10.7150/thno.100597. (1区，IF = 12.4, 通讯作者)

[2] K. W. Liu, Y. Q. Peng, M. H. Xu, K. Yuan, Y. C. Li, C. M. Lin, X. L. Zhao, J. Zhu, Y. Chang, Z. Z. Lin, S. Y. Pan, H. R. Ma*, X. R. Wang*, K. B. Huang*, "Brain-Targeted 9-Phenanthrol-Loaded Lipid Nanoparticle Prevents Brain Edema after Cerebral Ischemia-Reperfusion Injury by Inhibiting the Trpm4 Channel in Mice", Advanced Functional Materials, 2024, 2401173-2401191. (1区，IF = 18.5, 通讯作者)

[3] K. Yuan^#, K. R. Lai^#, G. F. Miao^#, J. B. Zhang, X. X. Zhao, G. Z. Tan, X. W. Wang*, and X. R. Wang*, "Cholinized-Polymer Functionalized Lipid-Based Drug Carrier Facilitate Liver Fibrosis Therapy Via Ultrafast Liver-Targeting Delivery", Biomacromolecules, 2024, 25, 10, 6526-6538. (1区，IF = 5.5, 通讯作者)

[4] G. F. Miao¹, Y. J. He¹, K. R. Lai, Y. Zhao, P. Y. He, G. Z. Tan, X. R. Wang*, "Accelerated blood clearance of PEGylated nanoparticles induced by PEG-based pharmaceutical excipients", Journal of Controlled Release, 2023, 363, 12-26. (1区，IF = 10.800, 通讯作者)

[5] G. F. Miao,^† Y. J. He,^† Z. H. Shang, P. Y. He, M. H. Xu, X. X. Zhao, and X. R. Wang*, "Combined Effects of Core Rigidity and Surface Charge of Polymeric Nanomicelles on the Cellular Uptake Efficiency", Macromolecules, 2023, 56, 7663-7674. (1区，IF = 5.500, 通讯作者)

[6] Y. Wang, K. Yuan, Z. H. Shang, G. Z. Tan, Q. J. Zhong , Y. J. He, G. F. Miao, K. R. Lai, Y. L. Li, X. R. Wang*, "Construction of nanohydrogels for enhanced delivery of hydrophilic and hydrophobic drugs and improving chemotherapy efficacy", European Polymer Journal, 2023, 186, 111838-111846. (2区，IF = 5.546, 通讯作者)

[7] G. Z. Tan, Y. Wang, Y. J. He, G. F. Miao, Y. Li, X. R. Wang*, "Bioinspired poly(cation-π) micelles drug delivery platform for improving chemotherapy efficacy", Journal of Controlled Release, 2022, 349, 486-501. (1区，IF = 11.467, 通讯作者)

[8] X. R. Wang, J. M. Hu*, S. Y. Liu*, "Overcoming the Dilemma of Permeability and Stability of Polymersomes through Traceless Cross-Linking", Accounts of Chemical Research, 2022, 55, 3404-3416. (1区，IF = 24.466, 第一作者)

[9] X. P. Song, X. R. Wang, J. Zhang, S. Shen, W. M. Yin, G. L. Ye, L. Y. Wang, H. H. Hou, X. Z. Qiu*, "A tunable self-healing ionic hydrogel with microscopic homogeneous conductivity as a cardiac patch for myocardial infarction repair", Biomaterials, 2021, 273, 120811-120821. (1区，IF = 15.304, 共同一作)

[10] X. R. Wang, C. Z. Yao, G. Y. Zhang, and S. Y. Liu*, "Regulating Vesicle Bilayer Permeability and Selectivity via Stimuli-Triggered Polymersome-to-PICsome Transition", Nature Communications, 2020, 11, 1524-1536. (1区，IF = 17.694, 第一作者)

[11] X. R. Wang, J. M. Hu, G. H. Liu, J. Tian, H. J. Wang, M. Gong, and S. Y. Liu*, "Reversibly Switching Bilayer Permeability of Photochromic Polymersomes Synergistically Stabilized via Cooperative Noncovalent Interactions", Journal of the American Chemical Society, 2015, 137, 15262-15275. (1区，IF = 16.383, 第一作者)

[12] X. R. Wang, J. M. Hu, G. Y. Zhang, S. Y. Liu*, "Highly Selective Fluorogenic Multianalyte Biosensors Constructed via Enzyme-Catalyzed Coupling and Aggregation-Induced Emission", Journal of the American Chemical Society, 2014, 136, 9890-9893. (1区，IF 16.383, ESI Highly cited paper, 第一作者)

[13] X. R. Wang, G. H. Liu, J. M. Hu, G. Y. Zhang, S. Y. Liu*, "Concurrent Block Copolymer Polymersome Stabilization and Bilayer Permeabilization via Stimuli-Regulated 'Traceless' Crosslinking", Angewandte Chemie International Edition, 2014, 53, 3138-3142. Highlighted by Nature Chemistry; DOI: 10.1038/nchem.1915. Highlighted by Materials Views China. (1区，IF 16.823, ESI Highly cited paper, 第一作者)