刘瑞源

姓名：刘瑞源

职称：教授

联系邮箱：ruiyliu@smu.edu.cn

v 学习经历

1992.9-1996.7 南昌大学，精细化工专业，学士

1997.6-2000.7 华南理工大学，精细化学工程专业，硕士

2006.10-2009.10 日本 京都大学，高分子化学专业，博士

v 工作经历

2000.08-2004.07 第一军医大学，助教

2004.08-2012.08 南方医科大学，讲师

2012.09-2022.01 南方医科大学，副教授

2022.01-至今    南方医科大学，教授  

v 研究方向

    申请者于主要从事近红外荧光分子探针的构建和生物应用，多模态分子影像探针的设计、制备及其应用。

v 主要学术任职

    无

v 主要获奖情况（科研获奖、人才类奖项）

    无

v 主要科研课题

1.广东省自然科学基金，主动靶向MR/光学双模态纳米探针的构建及对前列腺癌的靶向MR和荧光成像研究（2016A0303133546），2016-06-1至2019-06-1,10万；主持

2.国基自然科学基金面上项目，基于含TEMPO共轭聚合物的VEGFR-3靶向MR/光学双模态探针对非小细胞肺癌淋巴结转移诊断的研究(81671749) ,2017.01至2020.12，58万 ，主持

v 代表性论文

1. Zikang Chen, Yinuo Tu, Di Zhang, Chuang Liu, Yuping Zhou, Xiang Li, Xu Wu，Ruiyuan Liu*, A thermosensitive nanoplatform for photoacoustic imaging and NIR light triggered chemo-photothermal therapy Biomater. Sci., 2020, 8, 4299

2. Zikang Chen, Qi Xia, Yuping Zhou, Xipan Li, Li Qi, Qianjin Feng, Ruiyuan Liu*, Wufan Chen, 2-Dicyanomethylenethiazole based NIR absorbing organic nanoparticles for photothermal therapy and photoacoustic imaging, J. Mater. Chem. B, 2019, 7, 3950.

3. Kailun Deng, Lei Wang, Qi Xia, Ruiyuan Liu*, Jinqing Qu*, A turn-on fluorescent chemosensor based on aggregation-induced emission for cyanide detection and its bioimaging applications, Sensors & Actuators: B. Chemical, 2019, 296, 126645.

4.Qi Xia, Zikang Chen, Zhiqiang Yu, Lei Wang, Jinqing Qu, Ruiyuan Liu*，Aggregation-Induced Emission-Active Near-Infrared Fluorescent Organic Nanoparticles for Noninvasive Long-Term Monitoring of Tumor Growth, ACS Appl. Mater. Interfaces 2018, 10, 17081.

5.Lei Wang, Qi Xia, Ruiyuan Liu*, Jinqing Qu*, Real-time imaging of cancer cell generations and monitoring tumor growth using a nucleus targeted red fluorescent probe，J. Mater. Chem. B, 2018, 6, 2340.

6. Meirong Hou, Xiaodan Lu, Zhide Zhang, Qi Xia, Chenggong Yan, Zhiqiang Yu, Yikai Xu*,  Ruiyuan Liu*, Conjugated Polymer Containing Organic Radical for Optical/MR Dual-Modality Bioimaging, ACS Appl. Mater. Interfaces, 2017, 9, 44316.