张文泰

姓名：张文泰

职称：副研究员

联系邮箱：zhangwentai@smu.edu.cn

v 学习经历

2010.09-2014.06，西南交通大学，材料科学与工程专业，工学学士学位

2014.09-2021.07，西南交通大学，材料科学与工程专业，工学博士学位

2018.10-2019.01及2019.10-2020.01，德国图宾根大学，访问学者

v 工作经历

2021.07-2024.01，南方医科大学第十附属医院，博士后

2024.07-至今，南方医科大学第十附属医院，副研究员

v 研究方向

1）面向中心静脉导管、肺插管及呼吸道支架等存在的凝血、细菌感染和组织异常增生等临床并发症问题，综合利用生物功能仿生表面化学新技术、新方法，结合病理学、医学、细胞学和生物学，开发具有长效抗凝、抗污、超润滑的功能仿生涂层。

2）聚焦动脉粥样硬化发病及发展机制，利用表面改性策略开发具有免疫调控功能的血管支架、药物球囊等植介入器械，实现病变血管再生修复。

v 招生方向

v 主要学术任职

国际期刊Smart Materials in Medicine（中国科技期刊卓越计划高起点新刊）管理编辑

v  主要科研课题

1、南方医科大学第十附属医院高层次人才支持与发展计划（项目号：G202404），医用器械表面生物抗污研究，2024/07-2028/06，100万，主持（在研）

2、国家自然科学基金--国际（地区）合作与交流项目（项目号：32261160372），具有时序调控病变血管再生修复功能的Janus血管支架研究，2023/01-2026/12，100万，主要参与人（在研）。

3、中国博士后科学基金面上资助（项目号：2022M721524），“有机-无机”原位转化时序性功能涂层改性可降解镁合金血管支架研究，2022/09-2024/09，8万，主持（结题）

4、广东省基础与应用基础研究基金-区域联合基金（青年基金项目）（项目号：2021A1515111035），一氧化氮催化和表面肝素化协同修饰构建内皮功能仿生支架研究，2021/10-2024/09，10万，主持（结题）

v 代表性论文

1. Jiahao Chen^#, An Li^#, Jingtao Dai, Qingyun Fu, Zhentao Yu, Shulan Xu*, Wentai Zhang*, Ping Li*. Optimal submicron roughness for balancing degradation behavior, immune modulation, and microbial adhesion on zinc-based barrier membranes. Biomaterials Advances. 2025;169:214146.

2. Tian Yue^#, Wentai Zhang^#, Haifeng Pei^#, Dunzhu Danzeng, Jian He, Jiali Yang, Yong Luo, Zhen Zhang, Shiqiang Xiong, Xiangbo Yang, Qisen Ji, Zhilu Yang*, Jun Hou*. Monascus pigment-protected bone marrow-derived stem cells for heart failure treatment. Bioactive Materials. 2024;42:270-283.

3. Wentai Zhang, Jiangling Zhang, Fangkun Hu, Wenxuan Wang, Zeyu Du, You Ke, Qing Ma, Xiaohui Mou*, Jing Lu*, Zhilu Yang*. Active dual-protein coating assisted by stepwise protein-protein interactions assembly reduces thrombosis and infection. Advanced Science. 2024:2310259.

4. Wentai Zhang, Linxian Cui, Chaoming Xie, Zeyu Du, Xiaohui Mou, Qing Ma, Wenjie Tian*, Zhilu Yang*. Glycocalyx-inspired dynamic antifouling surfaces for temporary intravascular devices. Biomaterials. 2024;304:122427.

5. Nan Lyu^#, Daihua Deng^#, Yuting Xiang, Zeyu Du, Xiaohui Mou, Qing Ma, Nan Huang, Jing Lu*, Xin Li, Zhilu Yang*, Wentai Zhang*. An insect sclerotization-inspired antifouling armor on biomedical devices combats thrombosis and embedding. Bioactive Materials. 2024;33:562-571.

6. Jiajia Wei^#, Wentai Zhang^#, Xiaohui Mou, Haotian Meng, Qing Ma, Wenxuan Wang, Xin Li*, Qiufen Tu, Wenjie Tian*, Nan Huang, Zhilu Yang*. Bioinspired hemostatic and anti-infective armor for wound healing assisted by metal-phenol-polyamine system. Advanced Functional Materials. 2024;34(4):2306267.

7. Junyu Qian^#, Haotian Qin^#, Peijie Zeng^#, Jiaming Hou, Xiaoshan Mo, Gang Shen, Hui Zeng, Wentai Zhang*, Yingqi Chen*, Guojiang Wan*. Metal-organic Zn-zoledronic acid and 1-hydroxyethylidene-1,1-diphosphonic acid nanostick-mediated zinc phosphate hybrid coating on biodegradable Zn for osteoporotic fracture healing implants. Acta Biomaterialia. 2023;166:685-704.

8. Junyu Qian^#, Wentai Zhang^#, Yingqi Chen, Peijie Zeng, Jiale Wang, Chao Zhou, Hui Zeng, Hongxun Sang, Nan Huang, Haijun Zhang*, Guojiang Wan*. Osteogenic and angiogenic bioactive collagen entrapped calcium/zinc phosphates coating on biodegradable Zn for orthopedic implant applications. Biomaterials Advances. 2022;136:212792.

9. Ping Li^#, Wentai Zhang^#, Sebastian Spintzyk, Ernst Schweizer, Stefanie Krajewski, Dorothea Alexander, Jingtao Dai*, Shulan Xu*, Guojiang Wan*, Frank Rupp. Impact of sterilization treatments on biodegradability and cytocompatibility of zinc-based implant materials. Materials Science and Engineering: C. 2021;130:112430.

10. Wentai Zhang^#, Ping Li^#, Gang Shen, Xiaoshan Mo, Chao Zhou, Dorothea Alexander, Frank Rupp, Jürgen Geis-Gerstorfer*, Haijun Zhang*, Guojiang Wan*. Appropriately adapted properties of hot-extruded Zn–0.5Cu–xFe alloys aimed for biodegradable guided bone regeneration membrane application. Bioactive Materials. 2021;6(4):975-989.

11. Wentai Zhang^#, Sheng Zhao^#, Xiaoshan Mo, Peng Xian, Shuai Tang, Junyu Qian, Gang Shen, Chao Zhou, Nan Huang, Haijun Zhang*, Guojiang Wan*. Mg ions incorporated phytic acid (PA) and zoledronic acid (ZA) of metal-organic complex coating on biodegradable magnesium for orthopedic implants application. Surface and Coatings Technology. 2021;413:127075.

12. Wentai Zhang^#, Ping Li^#, Bernd Neumann, Hanna Haag, Ming Li, Zeqian Xu, Chao Zhou, Lutz Scheideler, Hans-Peter Wendel, Haijun Zhang*, Jürgen Geis-Gerstorfer*, Guojiang Wan*. Chandler-Loop surveyed blood compatibility and dynamic blood triggered degradation behavior of Zn-4Cu alloy and Zn. Materials Science and Engineering: C. 2021;119:111594.

13. Ping Li^#, Junyu Qian^#, Wentai Zhang^#, Christine Schille, Ernst Schweizer, Alexander Heiss, Ulrich E. Klotz, Lutz Scheideler, Guojiang Wan*, Jürgen Geis-Gerstorfer. Improved biodegradability of zinc and its alloys by sandblasting treatment. Surface and Coatings Technology. 2021;405:126678.

14. Ping Li^#, Wentai Zhang^#, Jingtao Dai, Alexander Basileos Xepapadeas, Ernst Schweizer, Dorothea Alexander, Lutz Scheideler, Chao Zhou, Haijun Zhang, Guojiang Wan*, Jürgen Geis-Gerstorfer*. Investigation of zinc‑copper alloys as potential materials for craniomaxillofacial osteosynthesis implants. Materials Science and Engineering: C. 2019;103:109826.

15. Wentai Zhang, Qijun Liu, Yingqi Chen, Guojiang Wan. Anodic dissolution dictates the negative difference effect (NDE) of magnesium corrosion more in chemical pathway. Materials Letters. 2018;232:54-57.

16. Wentai Zhang^#, Yingqi Chen, Meiyun Chen, Sheng Zhao, Jinlong Mao, Ai Qu, Wei Li, Yuancong Zhao, Nan Huang, Guojiang Wan*. Strengthened corrosion control of poly (lactic acid) (PLA) and poly (ε-caprolactone) (PCL) polymer-coated magnesium by imbedded hydrophobic stearic acid (SA) thin layer. Corrosion Science. 2016;112:327-337.