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沈折玉

作者:  来源:   阅读量:  发布时间:2019-09-06 09:43:47


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姓名:沈折玉

职称:教授

联系邮箱:sz@smu.edu.cn


v 学习经历

1998.09-2002.07:北京工商大学,生物化工,学士

2002.09-2008.07:中国科学院过程工程研究所,生物化工,博士

2004.10-2006.03:日本群马大学,生物材料,联合培养生


v 工作经历

2008.09-2010.03:日本群马大学,医学部,博士后

2010.05-2012.04:澳大利亚阿德莱德大学,化学工程系,博士后

2012.04-2015.12:中国科学院宁波材料技术与工程研究所,副研究员,硕导

2015.12-2018.12:中国科学院宁波材料技术与工程研究所,项目研究员,博导

2018.12-2019.07:中国科学院宁波材料技术与工程研究所,研究员,博导

2016.07-2019.07:美国国立卫生研究院(NIH),高级访问学者

2019.08-至今:南方医科大学,教授,博导


v 研究方向

磁共振成像造影剂、分子影像探针、生物医用纳米材料、肿瘤靶向诊断与治疗






v 主要学术任职

中国抗癌协会,会员

中国抗癌协会CTC技术专家委员会,委员

中美纳米医学及纳米生物技术学会,会员

International Journal of Medical Nano Research,编辑委员会成员

Biochemical and Biophysical Journal of Neutron Therapy & Cancer Treatments,编辑顾问委员会成员


v 主要获奖情况

[1] 浙江省自然科学基金杰出青年科学基金,2018年。

[2] 宁波市领军与拔尖人才(第二层次),2017年。

[3] 中国科学院青年创新促进会会员,2016年。


v 主要科研课题

[1] 肿瘤诊断与治疗用有机无机复合纳米材料,南方医科大学海外高层次人才计划(第三层次),300万,2019.08-2022.12,在研。

[2] 癌症诊断与治疗用硼钆复合纳米粒子,国家自然科学基金国际(地区)合作与交流项目,199万,2017.09-2020.08,在研。


v 代表性论文

[1] Zhenni Wei, Zhenqi Jiang, Chunshu Pan, Jianbi Xia, Kaiwei Xu, Ting Xue, Bo Yuan, Ozioma Udochukwu Akakuru, Chengjie Zhu, Guilong Zhang, Zheng Mao, Xiaozhong Qiu*, Aiguo Wu*, Zheyu Shen*. Ten-Gram-Scale Facile Synthesis of Organogadolinium Complex Nanoparticles for Tumor Diagnosis. Small 2020, 16(11), 1906870. (Impact Factor: 11.459)

[2] Dahai Liu, Zijian Zhou, Xinyu Wang, Hongzhang Deng, Lin Sun, Haixin Lin, Fei Kang, Yong Zhang, Zhantong Wang, Weijing Yang, Lang Rao, Kuikun Yang, Guocan, Yu, Jianshi Du*, Zheyu Shen*, Xiaoyuan Chen*. Yolk-shell nanovesicles endow glutathione-responsive concurrent drug release and T1 MRI activation for cancer theranostics. Biomaterials 2020, 244, 119979. (Impact Factor: 10.317)

[3] Zheyu Shen, Ting Liu, Zhen Yang, Zijian Zhou, Wei Tang, Wenpei Fan*, Yijing Liu, Jing Mu, Ling Li, Vladimir I. Bregadze, Swadhin K. Mandal, Anna A. Druzina, Zhenni Wei, Xiaozhong Qiu*, Aiguo Wu*, Xiaoyuan Chen*. Small-sized gadolinium oxide based nanoparticles for high-efficiency theranostics of orthotopic glioblastoma. Biomaterials 2020, 235, 119783. (Impact Factor: 10.317)

[4] Zijian Zhou, Zheyu Shen*, Xiaoyuan Chen*. Tale of Two Magnets: An Advanced Magnetic Targeting System. ACS Nano 2020, 14, 7-11. (Impact Factor: 14.588)

[5] Zheyu Shen, Wenpei Fan*, Zhen Yang, Yijing Liu, Vladimir I. Bregadze, Swadhin K. Mandal, Bryant C. Yung, Lisen Lin, Ting Liu*, Wei Tang, Lingling Shan, Yuan Liu, Shoujun Zhu, Sheng Wang, Weijing Yang, L. Henry Bryant, Duong T. Nguyen, Aiguo Wu*, Xiaoyuan Chen*. Exceedingly Small Gadolinium Oxide Nanoparticles with Remarkable Relaxivities for Magnetic Resonance Imaging of Tumors. Small 2019, 15, 1903422. (Impact Factor: 11.459)

[6] Jinbing Xie, Zheyu Shen*, Yasutaka Anraku, Kazunori Kataoka*, Xiaoyuan Chen*. Nanomaterial-Based Blood-Brain-Barrier (BBB) Crossing Strategies. Biomaterials 2019, 224, 119491. (Impact Factor: 10.317)

[7] Wenpei Fan, Nan Lu, Zheyu Shen*, Wei Tang, Bo Shen, Zhaowen Cui, Lingling Shan, Zhen Yang, Zhantong Wang, Orit Jacobson, Zijian Zhou, Yijing Liu, Ping Hu, Weijing Yang, Jibin Song, Yang Zhang, Liwen Zhang, Niveen M. Khashab, Maria Aronova, Guangming Lu*, Xiaoyuan Chen*. Generic synthesis of small-sized hollow mesoporous organosilica nanoparticles for oxygen-independent X-ray-activated synergistic therapy. Nat. Commun. 2019, 10, 1241. (Impact Factor: 12.121)

[8] Zheyu Shen, Ting Liu, Yan Li, Joseph Lau, Zhen Yang, Wenpei Fan, Zijian Zhou, Changrong Shi, Chaomin Ke, Vladimir I. Bregadze, Swadhin K. Mandal, Yijing Liu*, Zihou Li, Ting Xue, Guizhi Zhu, Jeeva Munasinghe, Gang Niu, Aiguo Wu*, Xiaoyuan Chen*. Fenton-reaction-acceleratable magnetic nanoparticles for ferroptosis therapy of orthotopic brain tumors. ACS Nano 2018, 12, 11355-11365. (Impact Factor: 14.588)

[9] Yijing Liu, Zhen Yang, Xiaolin Huang, Guocan Yu, Sheng Wang, Zijian Zhou, Zheyu Shen*, Wenpei Fan, Yi Liu, Matthew Davisson, Heather Kalish, Gang Niu, Zhihong Nie*, Xiaoyuan Chen*. Glutathione-responsive self-assembled magnetic gold nanowreath for enhanced tumor imaging and imaging-guided photothermal therapy. ACS Nano 2018, 12, 8129-8137. (Impact Factor: 14.588)

[10] Zheyu Shen, Jibin Song, Zijian Zhou, Bryant C. Yung, Maria A. Aronova, Yan Li, Yunlu Dai, Wenpei Fan, Yijing Liu*, Zihou Li, Huimin Ruan, Richard D. Leapman, Lisen Lin, Gang Niu, Xiaoyuan Chen*, Aiguo Wu*. Dotted core-shell nanoparticles for T1-weighted MRI of tumors. Adv. Mater. 2018, 30(33), 1803163. (Impact Factor: 27.398)[11] Yuanzhi Xia#, Xuehua Ma#, Junhua Gao, Guoxin Chen, Zihou Li, Xiaoxia Wu, Zhangsen Yu, Jie Xing, Li Sun, Huimin Ruan, Lijia Luo, Lingchao Xiang, Chen Dong, Wenzhi Ren, Zheyu Shen*, Aiguo Wu*. A flexible caterpillar-like gold nanoparticle assemblies with ultra-small nanogaps for enhanced dual-modal imaging and photothermal therapy. Small 2018, 14, 1800094. (Impact Factor: 11.459)

[12] Zheyu Shen, Jibin Song, Bryant C. Yung, Zijian Zhou*, Aiguo Wu*, Xiaoyuan Chen*. Emerging strategies of cancer therapy based on ferroptosis. Adv. Mater. 2018, 30, 1704007. (Impact Factor: 27.398)

[13] Zheyu Shen, Tianxiang Chen, Xuehua Ma, Wenzhi Ren, Zijian Zhou, Guizhi Zhu, Ariel Zhang, Yijing Liu, Jibin Song*, Zihou Li, Huimin Ruan, Wenpei Fan, Lisen Lin, Jeeva Munasinghe, Xiaoyuan Chen*, Aiguo Wu*. Multifunctional theranostic nanoparticles based on exceedingly small magnetic iron oxide nanoparticles for T1-weighted magnetic resonance imaging and chemotherapy. ACS Nano 2017, 11, 10992-11004. (Impact Factor: 14.588)

[14] Zheyu Shen, Aiguo Wu*, Xiaoyuan Chen*. Current detection technologies for circulating tumor cells. Chem. Soc. Rev. 2017, 46, 2038-2056. (Impact Factor: 42.846, inside front cover)

[15] Zheyu Shen, Hao Wu, Sugeun Yang, Xuehua Ma, Zihou Li, Mingqian Tan*, Aiguo Wu*. A novel Trojan-horse targeting strategy to reduce the non-specific uptake of nanocarriers by non-cancerous cells. Biomaterials 2015, 70, 1-11. (Impact Factor: 10.317)


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