研究方向

本系主要研究方向为传染病流行病学、分子流行病学、老年流行病学、医学大数据研究、临床流行病学和评价流行病学。

科研项目

本系主要科研方向为感染性疾病流行病学、管理和评价流行病学、临床流行病学、分子流行病学、老年流行病学、医学大数据等。承担了国家、军队和省市科研课题和横向合作项目共67项，累计资助经费：3100多万。

主要科研课题如下：

科研成果、专利

科研奖励：

1. 国家科技进步三等奖1项

2. 军队科技进步二等奖3项

3. 军队科技进步三等奖6项

4. 广东省科技进步二等奖3项

专利：

1. 一种伊蚊的诱捕、诱卵器（实用新型，授权公告号：CN201238543Y）

2. 淡水鱼粪便中香港海鸥型菌的检测方法（发明专利，专利公开号：CN101519691A）

3. 用于高通量抗体快速检测的荧光素酶免疫吸附方法（发明专利，专利公开号：CN107884371A）

4. 用于区分HIV-1新近与慢性感染的免疫吸附检测方法（发明专利，专利公开号：CN108828214A）

5. 一种海藻酸钠-壳聚糖P-VP8*IgY微胶囊制备方法及微胶囊（发明专利，专利公开号：CN107961228A）

6. 一种GII.4型诺如病毒广谱单克隆抗体的制备方法及用途（发明专利，专利公开号：N109734801A）

7.  HIV-1 RNA定量检测的实时荧光定量PCR引物和探针及其应用（发明专利，专利公开号：CN109722491A）

科研专著、论文

科研专著：

1. 主编《军队流行病学》，全军高等医学院教材（临床医学专业本科用），人民军医出版社，1994

2. 主编《医学生考试指导丛书-流行病学分册》，人民军医出版社，2004

3. 主编《常见传染病防治》（部队卫生防疫丛书），军事医学科学出版社，2006

4. 主编《现代热带医学》，2012，军事医学科学出版社,

5. 副主编《军事预防医学概论》，人民军医出版社，2006

6. 主编《临床流行病学》，2004，本校内部使用

7. 主编《流行病学实习教材》，2000，本校内部使用

8. 主编《Epi I Info流行病学软件应用教程》，2005，本校内部使用

9. 参编《军队流行病学》，全军高等医学院教材（临床医学专业本科用），人民军医出版社，1994

10. 参编《SPSS8.0统计软件应用教程》，2000，人民军医出版社

11. 参编《SPSS10.0统计软件应用教程》，2002，人民军医出版社

12. 参编《SPSS10.0统计软件高级应用教程》，2004，人民军医出版社

13. 参编《流行病学》（第六版），普通高等教育“十一五”国家级规划教材，人民卫生出版社，2007

14. 参编《现代流行病学》，人民卫生出版社，2007

15. 主编《现代热带医学》，北京：军事医学科学出版社，2012

16. 主编《流行病学》，北京大学医学出版社，2013

17. 参编《系统综述与Meta分析》，北京：人民卫生出版社，2017

18. 副主编《老年卫生学》，北京：科学出版社，2018

学术论文（近三年）：

1. Li ZH, Zhang XR, Lv YB, Shen D, Li FR, Zhong WF, Huang QM, Wu XB, Zeng Y, Gao X, Shi XM, Mao C. Leisure Activities and All-Cause Mortality Among the Chinese Oldest-Old Population: A Prospective Community-Based Cohort Study. J Am Med Dir Assoc. 2019 Oct 3. pii: S1525-8610(19)30612-7. doi: 10.1016/j.jamda.2019.08.003. （IF=4.899，1区）

2. Yuan JQ, Lv YB, Chen HS, Gao X, Yin ZX, Wang WT, Kraus VB, Luo JS, Wang JN, Zeng Y, Mao C, Shi XM. Association Between Late-Life Blood Pressure and the Incidence of Cognitive Impairment: A Community-Based Prospective Cohort Study. J Am Med Dir Assoc. 2019, 20(2):177-182.e2. （IF=4.899，1区）

3. Xiong YQ, You FF, Chen XJ, Chen YX, Wen YQ, Chen Q. Detection and phylogenetic analysis of porcine bocaviruses carried by murine rodents and house shrews in China. Transbound Emerg Dis. 2019, 66(1):259-267. （IF=3.554，1区）

4. Lv YB, Kraus VB, Gao X, Yin ZX, Zhou JH, Mao C, Duan J, Zeng Y, Brasher MS, Shi WY, Shi XM. Higher dietary diversity scores and protein-rich food consumption were associated with lower risk of all-cause mortality in the oldest old. Clinical Nutrition. 2019. （IF=6.402，1区）

5. Li FR, Zhang XR, Zhong WF, Li ZH, Gao X, Kraus VB, Lv YB, Zou MC, Chen GC, Chen PL, Zhang MY, Kur AKA, Shi XM, Wu XB, Mao C. Glycated Hemoglobin and All-Cause and Cause-Specific Mortality Among Adults With and Without Diabetes. J Clin Endocrinol Metab. 2019, 104(8):3345-3354.（IF=5.605，2区）

6. Li ZH, Lv YB, Zhong WF, Gao X, Byers Kraus V, Zou MC, Zhang XR, Li FR, Yuan JQ, Shi XM, Wu XB, Mao C. High-Density Lipoprotein Cholesterol and All-Cause and Cause-Specific Mortality Among the Elderly. J Clin Endocrinol Metab. 2019, 104(8):3370-3378.（IF=5.605，2区）

7. Mao C, Li ZH, Lv YB, Gao X, Kraus VB, Zhou JH, Wu XB, Shi WY, Li FR, Liu SM, Yin ZX, Zeng Y, Shi XM. Specific Leisure Activities and Cognitive Functions Among the Oldest-Old: the Chinese Longitudinal Healthy Longevity Survey. J Gerontol A Biol Sci Med Sci. 2019, pii: glz086.（IF=4.711，2区）

8. Zhang PD, Lv YB, Li ZH, Yin ZX, Li FR, Wang JN, Zhang XR, Zhou JH, Wu XB, Duan J, Mao C, Shi XM. Age, period and cohort effects in activities of daily living, physical and cognitive functioning impairment among the oldest-old in China. J Gerontol A Biol Sci Med Sci. 2019, pii: glz196.（IF=4.711，2区）

9. Li ZH, Lv YB, Kraus VB, Yin ZX, Liu SM, Zhang XC, Gao X, Zhong WF, Huang QM, Luo JS, Zeng Y, Ni JD, Mao C, Shi XM. Trends in the Incidence of Activities of Daily Living Disability Among Chinese Elderly from 2002-2014. J Gerontol A Biol Sci Med Sci. 2019 Oct 11. pii: glz221.（IF=4.711，2区）

10. Mao C, Li FR, Yin ZX, Lv YB, Luo JS, Yuan JQ, Mhungu F, Wang JN, Shi WY, Zhou JH, Chen GC, Gao X, Kraus VB, Wu XB, Shi XM. Plasma 25-Hydroxyvitamin D Concentrations Are Inversely Associated with All-Cause Mortality among a Prospective Cohort of Chinese Adults Aged ≥80 Years. J Nutr. 2019, 149(6):1056-1064. （IF=4.416，2区）

11. Lv YB, Mao C, Gao X, Yin ZX, Kraus VB, Yuan JQ, Zhang J, Luo JS, Zeng Y, Shi XM. Triglycerides Paradox Among the Oldest Old: "The Lower the Better?" . J Am Geriatr Soc. 2019, 67(4):741-748. （IF=4.113，2区）

12. Li FR, Wu X, Yuan J, Wang J, Mao C, Wu X. Comparison of thoracic endovascular aortic repair, open surgery and best medical treatment for type B aortic dissection: A meta-analysis. Int J Cardiol. 2018, 250:240-246. （IF=3.471，2区）

13. Li ZH, Zhong WF, Lv YB, Kraus VB, Xiang Gao X, Chen PL, Huang QM, Ni JD, XM, Mao C, Wu XB. Associations of plasma high-sensitivity Creactive protein concentrations with all-cause and cause-specific mortality among middle-aged and elderly individuals. Immunity & Ageing. 2019, 16:28. （IF=4.250，3区）

14. Shui JW, Liu WP, Liang YH, Zhang J, Wan ZW, Wang HY, Qu XW, Tang SX. Infection of human pegivirus 2 (HPgV-2) is associated with hepatitis C virus but not hepatitis B virus infection in people who inject drugs. J Gen Virol. 2019, 100(6):968-974. （IF=2.809，3区）

15. Wang HY, Cai QD, Liang YH, Shui JW, Tang SX. A simple and high-throughput luciferase immunosorbent assay for both qualitative and semi-quantitative detection of anti-HIV-1 antibodies. Virus Res. 2019, 263:9-15. （IF=2.736，3区）

16. Cai QD, Wang HY, Huang LP, Yan HC, Zhu WC, Tang SX. Characterization of HIV-1 genotype specific antigens for the detection of recent and long-term HIV-1 infection in China. Virus Res. 2019, 264:16-21. （IF=2.736，3区）

17. Mao C, Yuan JQ, Lv YB, Gao X, Yin ZX, Kraus VB, Luo JS, Chei CL, Matchar DB, Zeng Y, Shi XM. Associations between superoxide dismutase, malondialdehyde and all-cause mortality in older adults: a community-based cohort study. BMC Geriatr. 2019, 19(1):104. （IF=2.818，3区）

18. Lv YB, Mao C, Yin ZX, Li FR, Wu XB, Shi XM. Healthy Ageing and Biomarkers Cohort Study (HABCS): a cohort profile. BMJ Open. 2019, 9: e026513. (IF=2.376，3区)

19. Qiu MS, Wang XW, Yao Y, Ge SQ, Liu HM, Dai YC, Zhou Y. Protocol of Jidong Women Health Cohort Study: Rationale, Design, and Baseline Characteristics. Biomed Environ Sci. 2019, 32(2):144-152. （IF=1.917，3区）

20. He WQ, Chen XJ, Wen YQ, Li YZ, He H, Chen Q. Detection of Hepatitis B Virus-Like Nucleotide Sequences in Liver Samples from Murine Rodents and Asian House Shrews. Vector Borne Zoonotic Dis. 2019. （IF=1.939，3区）

21. Lv YB, Gao X, Yin ZX, Chen HS, Luo JS, Brasher MS, Kraus VB, Li TT, Zeng Y, Shi XM. Revisiting the association of blood pressure with mortality in oldest old people in China: community based, longitudinal prospective study. BMJ. 2018 Jun 5;361:k2158. （IF=27.604，1区）

22. Wang HY, Wan ZW, Xu R, Guan YJ, Zhu NL, Li JP, Xie ZW, Lu AQ, Zhang FC, Fu YS, Tang SX. A Novel Human Pegivirus HPgV-2 (HHpgV-1) is Tightly Associated with HCV Infection and HCV/HIV-1 Co-Infection. Clin Infect Dis. 2018, 66(1):29-35. （IF=9.055，1区）

23. Wang HY, Wan ZW, Sun Q, Zhu NL, Li TY, Ren XQ, An XP, Deng SY, Wu Y, Li XF, Li L, Li JY, Tong YG, Tang SX. Second Human Pegivirus in Hepatitis C Virus-Infected and Hepatitis C Virus/HIV-1-Co-infected Persons Who Inject Drugs, China. Emerg Infect Dis. 2018, 24(5):908-911. （IF=7.185，1区）

24. Tang WP, Zhu NL, Wang HY, Gao YW, Wan ZW, Cai QD, Yu SY, Tang SX. Identification and genetic characterization of equine Pegivirus in China. J Gen Virol. 2018, 99(6):768-776. （IF=2.809，3区）

25. Xiong YQ, Mo Y, Chen MJ, Cai W, He WQ, Chen Q. Detection and phylogenetic analysis of torque teno virus (TTV) carried by murine rodents and house shrews in China. Virology. 2018, 516:189-195. （IF=2.657，3区）

26. Xiong YQ, Mo Y, Wen YQ, Cheng MJ, Huo ST, Chen XJ, Chen Q. Optical coherence tomography for the diagnosis of malignant skin tumors: a meta-analysis. J Biomed Opt. 2018, 23(2):1-10. （IF=2.555，3区）

27. Xu SQ, Zhang Y, Wang P, Liu W, Wu XB, Zhou JY. A statistical measure for the skewness of X chromosome inactivation based on family trios. BMC Genet. 2018, 19(1):109. （IF=2.547，3区）

28. He WQ, Wen Y, Xiong Y, Zhang M, Cheng M, Chen Q. The prevalence and genomic characteristics of hepatitis E virus in murine rodents and house shrews from several regions in China. BMC Vet Res. 2018, 14(1):414. （IF=1.792，3区）

29. Xiong YQ, Zhou JH, Zhang MY, You FF, Li DL, Chen Q. Presence of rat bocavirus in oropharyngeal and fecal samples from murine rodents in China. Arch Virol. 2018, 163(11):3099-3103. （IF=2.261，4区）

30. Yin D, Zhu YN, Wang KF, Wang J, Zhang XR, Han M, He YQ, Chen Q, Hu GF. Development and evaluation of a rapid recombinase polymerase amplification assay for the detection of human enterovirus 71. Arch Virol. 2018, 163(9):2459-2463. （IF=2.261，4区）

31. Zheng XY, Qiu M, Guan WJ, Li JM, Chen SW, Cheng MJ, Huo ST, Chen Z, Wu Y, Jiang LN, Chen Q.Viral metagenomics of six bat species in close contact with humans in southern China. Arch Virol. 2018, 163(1):73-88. （IF=2.261，4区）

32. Chen X, Shi T, Huang J, Xiao G, Huang J, Xiong Y, Li X, Chen H, Zheng X, Yu S, Chen Q. Molecular detection and phylogenetic analysis of human parechovirus in individuals with acute diarrhea and healthy controls in Guangzhou, China. J Med Virol. 2018, 90(9):1444-1452. （IF=2.049，4区）

33. Jiang XL, Zhong W, An H, Fu M, Chen Y, Zhang Z, Xiao Z. Attenuated DHEA and DHEA-S response to acute psychosocial stress in individuals with depressive disorders. J Affect Disord. 2017, 215:118-124. （IF=4.084，2区）

34. Wang Z, Zhu J, Liu Z, Liu Y, Zheng N, Feng M, Chen Q, Yu W, Jiang L, Hu J. Multi-locus sequence typing of Laribacter hongkongensis isolates from freshwater animals, environment and diarrhea patients in southern China. Int J Food Microbiol. 2017, 245:98-104. （IF=4.006，2区）

35. Wu Y, Ren X, Yin D, Wang HY, Wan Z, Li X, Hu GF, Tang SX. Characterization of a novel HIV-1 unique recombinant form between CRF07_BC and CRF55_01B in men who have sex with men in Guangzhou, China. PLoS One. 2017, 12(4):e0175770.（IF=2.776，3区）

36. Wu Y, Wang HY, Ren X, Wan Z, Hu GF, Tang SX. HIV-1 CRF07_BC with a Seven Amino Acid Deletion in the gag p6 Region Dominates in HIV-1-Infected Men Who Have Sex with Men in China. AIDS Res Hum Retroviruses. 2017, 33(9):977-983. （IF=1.085，4区）