边东

姓名：边东

职称：副研究员

联系邮箱：biandong1990@163.com

v 学习经历：

2013.09-2018.07 北京大学 力学（先进材料与力学）专业 博士

2009.09-2013.07 中国矿业大学（北京） 材料科学与工程专业 学士

v 工作经历

2020.04-至今 广东省人民医院 医学研究部 助理研究员/副研究员

2018.10-2020.02 先健科技（深圳）有限公司&北京大学 校企联合博后

v 研究方向

生物材料，可降解金属材料及其植介入器械：

①高强/高塑、易腐蚀/耐腐蚀、刺激响应性金属；

②易熔/难熔金属的设计、先进制造及医学应用；

③小尺寸、全吸收、多功能、智能型植介入器械；

④材料与机体的物理、化学、力学及生物学适配关系；

⑤可降解金属材料及其植介入器械的产品化及应用转化。

v 招生方向

v 主要学术任职

广东省精准医学应用学会骨肿瘤分会委员

v  主要科研课题

1、国家自然科学基金委员会，区域创新发展联合基金重点项目，No.U22A20121，纳米晶可降解锌合金的设计制备及抗菌抗肿瘤机制，2023-01至2026-12，95万元，在研，联合单位主持

2、企业横向研发项目（合肥博雅迈特生物材料有限公司），No. 2024-102，可降解金属吻合钉在模拟体液中的降解行为研究，2024-09-01至2026-09-01，20万元，在研，主持

3、中华人民共和国科学技术部，十四五国家重点研发计划项目（诊疗装备与生物医用材料专项），No.2021YFC2400700，生物适配型可降解镁合金硬组织植入器械产品研发，2021-10至2025-12，1500万元，在研，参与

v 代表性论文

[1] Dong Bian# *, Zhipei Tong#, Gencheng Gong#, He Huang, Liudang Fang, Hongtao Yang, Wenda Gu*, Hui Yu*, Yufeng Zheng*, Additive Manufacturing of Biodegradable Molybdenum - From Powder to Vascular Stent, Advanced Materials, 36(32) (2024) 2401614. (IF=27.4)

[2] He Huang#, Liudang Fang#, Zhipei Tong, Gencheng Gong, Hui Yu, Olga Kulyasova, Ruslan Z. Valiev*, Dandan Xia*, Yufeng Zheng*, Dong Bian*, Nanostructuring of Zn-Li-based alloys through severe plastic deformation: microstructure, mechanical properties and corrosion behaviors, Nano Materials Science (2024) DOI: 10.1016/j.nanoms.2024.07.004. (IF=12.6)

[3] Qianying Jia, He Huang, Zhipei Tong, Liudang Fang, Qinggong Jia, Shijie Zhu, Yufeng Zheng*, Shaokang Guan*, Dong Bian*, Hui Yu*, Endothelium-Mimicking with NO-generating coating on bioabsorbable magnesium alloy for improving corrosion resistance and biological responses of vascular stents, Chemical Engineering Journal, 490 (2024) 151344. (IF=13.4)

[4] Zhipei Tong, Chuanqiang Li*, Dahui Liang, Mincong Chen, Yong Dong, Dong Bian*, Changjian Yan*, En Hou Han, Improving the corrosion resistance of an ultra-lightweight BCC Mg-Li-Zn alloy via controlling the microstructure by heat treatment, Journal of Magnesium and Alloys, (2024) DOI: 10.1016/j.jma.2024.07.028. (IF=15.8)

[5] Dong Bian#, Zhipei Tong#, Gencheng Gong#, He Huang, Guixing Cai, Xingchen Yan*, Hui Yu*, Cheng Chang*, Yufeng Zheng*, A spatiotemporal “bulk erosion” mode in selective laser melted magnesium alloys and the resulting adverse cell & tissue responses, Journal of Materials Science & Technology, 198 (2024) 243-258. (IF=11.2)

[6] Dong Bian#, Xiao Chu#, Jin Xiao#, Zhipei Tong#, He Huang, Qinggong. Jia, Jianing Liu, Wenting Li, Hui Yu, Yue He, Limin Ma, Xiaolan Wang, Mei Li, Tao Yang, Wenhan Huang, Chi Zhang, Mengyu Yao, Yu Zhang*, Zhigang Xu*, Shaokang Guan*, Yufeng Zheng*, Design of single-phased magnesium alloys with typically high solubility rare earth elements for biomedical applications: Concept and proof, Bioactive Materials, 22 (2023) 180-200. (IF=18.9)

[7] He Huang, Guannan Li, Qinggong Jia, Dong Bian*, Shaokang Guan, Olga Kulyasova, Ruslan Z. Valiev, Julietta V. Rau, Yufeng Zheng*, Recent advances on the mechanical behavior of zinc based biodegradable metals focusing on the strain softening phenomenon, Acta Biomaterialia, 152 (2022) 1-18. (IF=10.633)

[8] Dong Bian, Xiaochen Zhou, Jianing Liu, Wenting Li, Danni Shen, Yufeng Zheng*, Wenda Gu, Jingjun Jiang*, Mei Li, Xiao Chu, Limin Ma, Xiaolan Wang, Yu Zhang, Sander Leeflang, Jie Zhou*, Degradation behaviors and in-vivo biocompatibility of a rare earth- and aluminum-free magnesium-based stent, Acta Biomaterialia, 124 (2021) 382-397. (IF=10.633)

[9] Dong Bian#, Li Qin#, Wenjiao Lin, Danni Shen, Haiping Qi, Xiaoli Shi, Gui Zhang, Hongwei Liu, Han Yang, Jin Wang, Deyuan Zhang*, Yufeng Zheng*, Magnetic Resonance (MR) safety and compatibility of a novel iron bioresorbable scaffold, Bioactive Materials, 5 (2020) 260-274. (IF=14.593)

[10] Gencheng Gong*, He Huang, Zhipei Tong, Yufeng Zheng*, Dong Bian*, Yu Zhang*, Implant derived high local concentration of magnesium inhibits tumorigenicity of osteosarcoma, Biomaterials, 320 (2025) 123263. (IF=12.8)

[11] He Huang#, Gencheng Gong#, Hui Yu#, Zhipei Tong, Qinggong Jia, Liudang Fang, Shaokang Guan, Jingjun Nie, Dafu Chen*, Jing Bai*, Dong Bian*, Yufeng Zheng*, Impact of scandium on the microstructure, mechanical properties, corrosion behaviors and in-vitro biocompatibility of a Zn-0.1Li alloy, Journal of Materials Science & Technology, 229 (2025) 235-251. (IF=11.2)

[12] Zhipei Tong#, Gencheng Gong#, He Huang, Guixing Cai, Liudang Fang, Hui Yu, Chuanqiang Li*, Yufeng Zheng*, Dong Bian*, In-vitro corrosion and biocompatibility of additively manufactured biodegradable molybdenum, Acta Biomaterialia, 191 (2025) 66-79. (IF=9.4)