研究方向：
- 微生物组方法学 人体微生物组 环境微生物组
- 环境卫生饮水净化、毒理学及抗诱变方向的研究
- 有机磷农药的生殖毒性研究; 砷的生殖发育毒性与致癌机制研究
- 环境耐药基因的多样性、典型抗生素耐药菌的耐药机制研究
代表性课题：
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课题名称
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来源
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负责人
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金额
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微生物组研究方法学
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国家自然科学基金优秀青年科学基金（31322003）
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周宏伟
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100万元
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基于BIPES的微生物群落分析新方法研究
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国家自然科学基金面上项目（31270152）
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周宏伟
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82万元
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深海资源微生物多样性分析及数据库建设
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国际海域资源调查与开发“十二五”重大课题子课题（DY125-15-R-01）
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周宏伟
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80万元
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新世纪优秀人才
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教育部（NCET-11-0921）
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周宏伟
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50万元
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微生物群落结构分析新方法的实验偏差研究
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广东省教育厅科研处科技创新项目（2012KJCX0031）
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周宏伟
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14万元
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国家杰出青年科学基金培育计划
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南方医科大学
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周宏伟
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30万元
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饮用水深度净化消毒复合技术的推广应用
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广东省卫生厅适宜卫生技术推广应用重点项目
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叶卓明
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5万元
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有机磷农药通过细胞间隙连接通讯介导雌性生殖毒性及其机制研究
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教育部
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吴继国
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4万元
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有机磷农药通过细胞间隙连接通讯介导雌性生殖毒性及其机制研究
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广东省医学基金
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吴继国
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1万元
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广州市中小学食安全普及教育
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广州市科学技术局
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吴继国
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3万元
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红树林湿地微生物对典型抗生素的相应及耐药基因的筛选、克隆
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国家自然科学基金青年基金（31300114）
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蒋云霞
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23万元
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代表性文章：
- Wang Y, Sheng HF, He Y, Wu JY, Jiang YX, Tam NFY, and Zhou HW*（周宏伟，通讯作者） (2012) Comparison of the levels of bacterial diversity in freshwater, intertidal wetland, and marine sediments by using millions of Illumina tags. Applied and Environmental Microbiology. 78:8264-8271 (IF 3.829)
- Jiang XT, Zhang H, Sheng HF, Wang Y, He Y, Zou F, and Zhou HW* （周宏伟，通讯作者）(2012) Two-Stage Clustering (TSC): A pipeline for selecting operational taxonomic units for the high-throughput sequencing of PCR amplicons. PLoS ONE 7(1): e30230 (IF 4.35)
- Zhou HW*（周宏伟，通讯作者）, Li DF, Tam NF, Jiang XT, Zhang H, Sheng HF, Liu X, Qin J, and Zou F (2011) BIPES, a Cost-Effective High-Throughput Method for Assessing Microbial Diversity. The ISME Journal. 5:741-749 (IF 8.951)
- Jiang YX, Wu JG, Ai CX, Zou F, Zhou HW* （周宏伟，通讯作者）(2011) Integrated lysis protocol can reduced the DNA extraction bias on mangrove soil. Journal of Bioscience and Bioengineering 111: 153-157 (IF1.749)
- Lu SY, Zhang YL, Gen SN, Li TY, Ye ZM, Zhang DS, Zou F and Zhou HW* （周宏伟，通讯作者）(2010) High Diversity of Extended-spectrum Beta-lactamase-producing Bacteria in an Urban River Sediment Habitat. Applied and Environmental Microbiology 76: 5972-5976. (IF 3.73)
- Wu JY, Jiang XT, Jiang YX, Lu SY, Zou F, Zhou HW* （周宏伟，通讯作者）(2010) Effects of polymerase, template dilution and cycle number on PCR based 16S rRNA diversity analysis using the deep sequencing method. BMC Microbiology 10:255. (IF2.98)
- Lv ZR, Shi L, Wang J, Park D, Bhak J, Yang JM, Park YD, Zhou HW* （周宏伟，共同通讯作者）and Zou F* (2010) The effect of trifluoroethanol on tyrosinase activity and conformation: inhibition kinetics and computational simulations. Applied Biochemistry Biotechnology 160:1896-908 (IF 1.42)
- Wu JG, Jiang YX, Zha LY, Ye ZM, Zhou ZF, Ye JF, Zhou HW* （周宏伟，通讯作者）(2010) Tetracycline degradation by ozonation, and evaluation of biodegradability and toxicity of ozonation byproducts. Journal of Environmental Engineering and Science 37:1485-1491 (IF 0.402)
- 陆素颖，李天宇，周宏伟*（通讯作者） （2010）头孢噻肟处理的城市河流沉积物微生物群落结构及blaCTX-M多样性的研究。南方医科大学学报30: 463-467.
- Tao R, Ying GG, Su HC, Zhou HW(周宏伟) and Sidhuc JPS (2010) Detection of antibiotic resistance and tetracycline resistance genes in Enterobacteriaceae isolated from the Pearl rivers in South China. Environmental Pollution 158: 2101-2109
- Zhou HW(周宏伟), Wong HY, Yu MK, Park YD, Wong YS and Tam NF (2009) Polycyclic Aromatic Hydrocarbon-Induced Structural Shift of Bacterial Communities in Mangrove Sediment. Microbial Ecology 58: 153-160
- Li CH, Zhou HW(周宏伟), Wong YS and Tam NF (2009) Vertical distribution and anaerobic biodegradation of polycyclic aromatic hydrocarbons in mangrove sediments in Hong Kong, South China. Science of the Total Environment 407, 5772-5779
- Zhou HW(周宏伟), Luan TG, Zou F, Tam NF. (2008) Different bacterial groups for biodegradation of three- and four-ring PAHs isolated from a Hong Kong mangrove sediment. Journal of Hazardous Materials 152, 1179-1185
- Zhou HW(周宏伟), Guo CL, Wong YS and Tam NFY (2006) Genetic diversity of dioxygenase genes in PAH-degrading bacteria isolated from mangrove sediments. FEMS Microbiology Letters, 262, 148-157.
- Zhong, Y, Luan, TG, Zhou, HW(周宏伟), Lan, CY and Tam, NFY (2006) Pyrene intermediates production in single and binary PAH culture by a PAH-degrading Mycobacterium sp. isolated from mangrove sediment. Environmental Toxicology and Chemistry, 25, 2853-2859
- Luan TG, Yu KSH, Zhong Y, Zhou HW(周宏伟), Lan CY and Tam NFY (2006) Study of metabolites from the degradation of polycyclic aromatic hydrocarbons (PAHs) by bacterial consortium enriched from mangrove sediments. Chemosphere, 65, 2289-2296
- 张亚莉，周宏伟，马骊等，（2006）医患鼻前庭携带耐甲氧西林金黄色葡萄球菌与医院感染菌同源性的研究。南方医科大学学报, 26, 635-637
- Guo CL, Zhou HW(周宏伟), Wong YS and Tam NFY (2005) Isolation of PAH-degrading bacteria from mangrove sediments and their biodegradation potential. Marine Pollution Bulletin, 51, 1054-1061.
- Zhou HW(周宏伟), Park YD, and Zhou HM (2002) Lead ion effect on creatine kinase: equilibrium and kinetic studies of inactivation and conformational changes. International Journal of Biochemistry and Cell Biology 34(5):564-71.
- Zhou HW(周宏伟), Xu Y, and Zhou HM (2002) Activity and conformational changes of horseradish peroxidase in trifluoroethanol Biochemistry and Cell Biology. 80:205-13.
- Meng FG, Zhou HW(周宏伟), and Zhou HM (2001) Effects of acrylamide on creatine kinase from rabbit muscle. International Journal of Biochemistry and Cell Biology, 33, 1064-1070
- 叶卓明（通讯作者）.Kinetic, structural and molecular docking studies on the inhibition of tyrosinase induced by arabinose. International journal of biological macromolecules 2012.50(3):694-700（IF：2.502）
- 叶卓明（通讯作者）.Towards alpha-glucosidase folding induced by trifluoroethanol: Kinetics and computational prediction Process Biochemistry,2012. 47 (12): 2284–2290 (IF:2.627)
- 叶卓明（通讯作者）. Inhibitory effect of Zn2+ on -glucosidase: Inhibition kinetics and molecular dynamics simulation Process Biochemistry,2012. 47(12): 2510–2517(IF:2.627)
- Wu J, Jiang Y, Zha L, Ye Z, Zhou Z, Ye J, Zhou H. 2010. Tetracycline degradation by ozonation, and evaluation of biodegradability and toxicity of ozonation byproducts. Journal of Environmental Engineering and Science (Canadian Journal of Civil Engineering, 37(11):1485-1491)
- Wu J, Jiang Y, Zha L, Ye Z, Zhou Z, Ye J, Zhou H. 2010. Tetracycline degradation by ozonation, and evaluation of biodegradability and toxicity of ozonation byproducts. Journal of Environmental Engineering and Science (Canadian Journal of Civil Engineering, 37(11):1485-1491)
主要成果、专利：
军队科技进步二等奖 1项
军队科技进步三等奖 1项
广东省科技进步三等奖 1项
广东省优秀硕士论文 1项
国家授权专利 4项